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Integrative genomics viewer.整合基因组浏览器。
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Identification of a major determinant of mouse neurovirulence of dengue virus type 2 using stably cloned genomic-length cDNA.利用稳定克隆的基因组长度互补DNA鉴定登革2型病毒小鼠神经毒力的主要决定因素。
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实验室连续保存的四种血清型登革病毒原型株的全基因组序列

Complete Genome Sequences of Four Serotypes of Dengue Virus Prototype Continuously Maintained in the Laboratory.

作者信息

Chin-Inmanu Kwanrutai, Suttitheptumrong Aroonroong, Sangsrakru Duangjai, Mairiang Dumrong, Tangphatsornruang Sithichoke, Malasit Prida, Suriyaphol Prapat

机构信息

Division of Bioinformatics and Data Management for Research, Research Group and Research Network Division, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Center of Excellence in Bioinformatics and Clinical Data Management, Research Group and Research Network Division, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Microbiol Resour Announc. 2019 May 9;8(19):e00199-19. doi: 10.1128/MRA.00199-19.

DOI:10.1128/MRA.00199-19
PMID:31072897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6509522/
Abstract

Dengue prototype strains are widely used for virological study. The strains presented here have been cultured under different laboratory environments, resulting in accumulating genetic variations. We present the genomes of four serotypes of the dengue prototype strain that were continuously maintained in the laboratory. These genomes contain bases different from those of the original prototype strains in GenBank.

摘要

登革热原型毒株被广泛用于病毒学研究。这里展示的毒株是在不同实验室环境下培养的，导致积累了遗传变异。我们展示了在实验室中持续保存的登革热原型毒株四个血清型的基因组。这些基因组所含碱基与GenBank中原始原型毒株的碱基不同。