Mbuyi-Muamba J M, Dequeker J
Acta Anat (Basel). 1987;128(3):184-7. doi: 10.1159/000146337.
Using EDTA extraction procedure, compact and spongy bone from human femur, rib and iliac crest were compared in terms of their content in collagen, sialoprotein, proteoglycan and carbohydrate. The bone matrix sizes displayed significant variations, the femur having the smallest size and iliac crest the largest one. No significant difference in the matrix size has been found between the spongy and compact bone. The EDTA extractability of the spongy bone was higher than that of the compact bone, with femur showing the lowest extractability. The collagen content of the 3 bones studied was similar although the femur had slightly lower values. The sialic and uronic acids and hexose contents were higher in the femur than in the rib and iliac crest. The collagen/hexose, collagen/sialic acid and collagen/uronic acid ratios in the bone matrix were highest in the iliac crest and lowest in the femur, suggesting that alterations in the amounts of bone matrix can affect the mechanical properties of different parts of the bony skeleton and vice versa.
采用乙二胺四乙酸（EDTA）提取法，对取自人股骨、肋骨和髂嵴的密质骨和松质骨的胶原蛋白、涎蛋白、蛋白聚糖和碳水化合物含量进行了比较。骨基质大小存在显著差异，股骨的骨基质大小最小，髂嵴的最大。松质骨和密质骨之间未发现基质大小有显著差异。松质骨的EDTA可提取性高于密质骨，股骨的可提取性最低。所研究的3种骨的胶原蛋白含量相似，不过股骨的值略低。股骨中的唾液酸、糖醛酸和己糖含量高于肋骨和髂嵴。骨基质中的胶原蛋白/己糖、胶原蛋白/唾液酸和胶原蛋白/糖醛酸比值在髂嵴中最高，在股骨中最低，这表明骨基质数量的改变会影响骨骼不同部位的力学性能，反之亦然。
