Lomnitzer R, Rabson A R
Clin Exp Immunol. 1978 Sep;33(3):499-502.
Normal lymphocytes treated with trypsin lost their ability to form normal numbers of rosettes with sheep red blood cells. The recovery in E-rosette forming capacity of trypsinized cells was considerably augmented when the cells were incubated in the presence of a wide range of concentrations of the immunostimulatory drug, levamisole. Substantial recovery of rosette-forming ability was seen 2 hr after incubation of trypsinized cells with levamisole.
用胰蛋白酶处理的正常淋巴细胞失去了与绵羊红细胞形成正常数量玫瑰花结的能力。当在广泛浓度范围内的免疫刺激药物左旋咪唑存在下孵育细胞时,胰蛋白酶处理细胞的E玫瑰花结形成能力的恢复显著增强。在用左旋咪唑孵育胰蛋白酶处理的细胞2小时后,可见玫瑰花结形成能力有实质性恢复。