De Cock W, De Cree J, Verhaegen H
Immunology. 1978 Aug;35(2):223-7.
Aggregated human IgG significantly inhibited the E-rosette formation of T lymphocytes of healthy subjects and cancer patients. The aggregated IgG induced inhibition of rosette forming cells depended on the time of preincubation at 37 degrees. Levamisole, an anti-anergic chemotherapeutic agent, could partly but significantly prevent the aggregated IgG induced inhibition of the E-rosette formation.
聚集的人IgG显著抑制健康受试者和癌症患者T淋巴细胞的E花环形成。聚集的IgG诱导的花环形成细胞抑制作用取决于在37℃预孵育的时间。左旋咪唑,一种抗无反应性化疗药物,可部分但显著地防止聚集的IgG诱导的E花环形成抑制。