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同种异体骨楔形块在胫骨高位内侧开放楔形截骨术中用于大角度矫正的生物力学影响。

The biomechanical effects of allograft wedges used for large corrections during medial opening wedge high tibial osteotomy.

机构信息

Department of Sport, Exercise & Health, University of Winchester, Winchester, Hampshire, England.

Basingstoke and North Hampshire Hospital, Basingstoke, Hampshire, England.

出版信息

PLoS One. 2019 May 10;14(5):e0216660. doi: 10.1371/journal.pone.0216660. eCollection 2019.

Abstract

The inclusion of an allograft wedge during medial opening wedge high tibial osteotomy has been shown to lead to satisfactory time-to-union in larger corrections (>10°). Such large corrections are associated with greater incidences of intraoperative hinge fracture and reduced construct stability. The purpose of this study was to investigate the biomechanical stability that an allograft wedge brings to an osteotomy. Ten medium-size fourth generation artificial sawbone tibiae underwent 12 mm biplanar medial opening wedge high tibial osteotomy with a standard Tomofix plate. Five tibiae had an allograft wedge inserted into the osteotomy gap prior to plate fixation (allograft group). The gap in the remaining tibiae was left unfilled (control group). Each group underwent static compression testing and cyclical fatigue testing until failure of the osteotomy. Peak force, valgus malrotation, number of cycles, displacement and stiffness around the tibial head were analysed. Intraoperative hinge fractures occurred in all specimens. Under static compression, the allograft group withstood higher peak forces (6.01 kN) compared with the control group (5.12 kN). Valgus malrotation was lower, and stiffness was higher, in the allograft group. During cyclical fatigue testing, results within the allograft group were more consistent than within the control group. This may indicate more predictable results in large osteotomies with an allograft. Tibial osteotomies with allograft wedges appear beneficial for larger corrections, and in cases of intraoperative hinge fracture, due to the added construct stability they provide, and the consistency of results compared with tibial osteotomies without a graft.

摘要

在进行内侧开放楔形胫骨高位截骨术中加入同种异体骨楔形块,已被证明可在较大的矫正角度 (>10°)下实现满意的愈合时间。这种较大的矫正角度与术中铰链骨折的发生率增加和结构稳定性降低有关。本研究旨在探讨同种异体骨楔形块为截骨术带来的生物力学稳定性。10 个中等大小的第四代人工锯骨胫骨进行了 12mm 双平面内侧开放楔形胫骨高位截骨术,使用标准的 Tomofix 板固定。5 个胫骨在使用钢板固定前将同种异体骨楔形块插入截骨间隙(同种异体组)。其余胫骨的间隙未填充(对照组)。每组都进行了静态压缩测试和循环疲劳测试,直到截骨失败。分析了胫骨头部周围的峰值力、外翻旋转、循环次数、位移和刚度。所有标本均发生术中铰链骨折。在静态压缩下,同种异体组的峰值力(6.01kN)高于对照组(5.12kN)。同种异体组的外翻旋转角度较低,刚度较高。在循环疲劳测试中,同种异体组的结果比对照组更一致。这可能表明在较大的截骨术中,同种异体移植具有更可预测的结果。带有同种异体骨楔形块的胫骨截骨术对于较大的矫正角度是有益的,并且在术中发生铰链骨折的情况下,由于其提供的额外结构稳定性以及与无移植胫骨截骨术相比结果的一致性,也是有益的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0693/6510412/22cc54bc0cc5/pone.0216660.g001.jpg

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