Patras Highest Institute of Education and Technology, Patras, Greece.
Department of Otolaryngology, Beijing Electric Power Hospital, Beijing, China.
Clin Ther. 2019 Jun;41(6):1222-1226. doi: 10.1016/j.clinthera.2019.04.010. Epub 2019 May 7.
To review evidence of hypersensitivity reactions to allergens and/or pathogens transmitted via intimate contact.
We reviewed PubMed for publications in English between 1980 and 2018 using the terms allergy, drugs, foods, hypersensitivity, intercourse, kissing, Kounis syndrome, mast cells, and semen.
In human RELATIONSHIPS, intimate contact can occasionally have disastrous or even fatal consequences because antigens and pathogens can be transmitted via the oral and vaginal mucosa. Hypersensitivity to semen is an underrecognized problem. Some individuals also developed acute coronary hypersensitivity, which mimics myocardial infarction, known as Kounis syndrome.
Hypersensitivity reactions to allergens and/or pathogens via intimate contact are common and should be recognized. Sensitive patients should be evaluated for atopic diathesis because such patients may be more susceptible and could also develop Kounis syndrome.
回顾通过亲密接触传播的过敏原和/或病原体引起的过敏反应的证据。
我们检索了 1980 年至 2018 年期间在 PubMed 上发表的英文文献，使用了过敏、药物、食物、过敏反应、性交、亲吻、Kounis 综合征、肥大细胞和精液等术语。
在人类的关系中，亲密接触偶尔会产生灾难性甚至致命的后果，因为抗原和病原体可以通过口腔和阴道黏膜传播。对精液过敏是一个未被充分认识的问题。一些人还出现了类似于心肌梗死的急性冠状动脉过敏反应，即 Kounis 综合征。
通过亲密接触引起的过敏原和/或病原体的过敏反应很常见，应该得到认识。敏感患者应评估特应性素质，因为此类患者可能更容易受到影响，并且也可能发展为 Kounis 综合征。
