Guo Qiaoyun, Xie Weihong, Peng Rui, Ma Yan, Chong Feifei, Wang Yanli, Song Mengmeng, Ye Hua, Wang Peng, Wang Kaijuan, Song Chunhua
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan, China; Henan Key Laboratory of Tumor Epidemiology, Zhengzhou, Henan, China.
Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital, Zhengzhou University, Zhengzhou, Henan, China.
J Stroke Cerebrovasc Dis. 2019 Jul;28(7):1841-1852. doi: 10.1016/j.jstrokecerebrovasdis.2019.04.016. Epub 2019 May 7.
The aim was to investigate the relationship between sleep duration and stroke according to nonhealth status among adults in Central China.
A total of 18,670 participants were selected by stratified multistage random sampling method in Henan province during 2013-2015. Restricted cubic splines and logistic regression were used to calculate the association between sleep duration and stroke.
Sleep duration showing a J-shaped dose-response association with risk of stroke among the Chinese adults in the study. The respective percentages of stroke were 6.2%, 5.6%, 3.5%, 4.5%, 5.6%, and 9.2% for those whose sleep duration less than 6 h/day, 6∼7 h/day, 7∼8 h/day, 8∼9 h/day, 9∼10 h/day, and more than or equal to 10 h/day. Compared with sleep duration of 7∼8 h/day, the risk of stroke increased by 37% (95% confidence interval [CI]: 8%, 73%) and 63% (95% CI: 30%, 104%) for those whose sleep duration were 9∼10 h/day and more than or equal to 10 h/day. The correlations between sleep durations and stroke seemed to be stronger in men than women. Stroke was associated with shorter sleep duration in ageing 60-88 years, instead of 18-59 years. The correlation between sleep duration and stroke was statistically significant at lower education level. Furthermore, the risk of stroke was slightly higher in urban residents than rural residents.
In summary, a J-shaped dose-response association between sleep duration and stroke was found among the adults in Central China. Furthermore, people who were male, older, less educated and living in urban areas had a higher risk of stroke.
旨在根据中国中部成年人的非健康状况，研究睡眠时间与中风之间的关系。
2013年至2015年期间，采用分层多阶段随机抽样方法在河南省共选取了18670名参与者。使用受限立方样条和逻辑回归来计算睡眠时间与中风之间的关联。
在该研究的中国成年人中，睡眠时间与中风风险呈J形剂量反应关系。睡眠时间小于6小时/天、6至7小时/天、7至8小时/天、8至9小时/天、9至10小时/天以及大于或等于10小时/天的人群中，中风的相应百分比分别为6.2%、5.6%、3.5%、4.5%、5.6%和9.2%。与睡眠时间为7至8小时/天相比，睡眠时间为9至10小时/天以及大于或等于10小时/天的人群中风风险分别增加37%（95%置信区间[CI]：8%，73%）和63%（95%CI：30%，104%）。睡眠时间与中风之间的相关性在男性中似乎比女性更强。中风与60至88岁年龄段的较短睡眠时间相关，而非18至59岁年龄段。在较低教育水平下，睡眠时间与中风之间的相关性具有统计学意义。此外，城市居民中风风险略高于农村居民。
总之，在中国中部成年人中发现睡眠时间与中风之间存在J形剂量反应关系。此外，男性、年龄较大、受教育程度较低以及居住在城市地区的人群中风风险较高。
