School of Life and Environmental Science, Department of Food and Life Science, Azabu University.
Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center.
J Epidemiol. 2020 May 5;30(5):227-235. doi: 10.2188/jea.JE20180262. Epub 2019 May 11.
Some Okinawan vegetables have been reported to have anti-diabetic activity; however, no prospective cohort study has clarified whether consumption of Okinawan vegetables is associated with a risk of type 2 diabetes. This study aimed to determine the association between consumption of Okinawan vegetables and risk of type 2 diabetes through a large-scale, population-based, prospective study in Japan.
We examined 10,732 participants (4,714 men and 6,018 women) aged 45-74 years who resided in Okinawa. Participants were asked to answer a 147-item food frequency questionnaire. We calculated the overall amount of Okinawan vegetables consumed and the amount of seven specific kinds of Okinawan vegetables consumed. The odds ratios (ORs) for self-reported type 2 diabetes during 5 years of follow-up were estimated via multivariate logistic regression analysis.
During the 5-year period, 216 new cases (123 men and 93 women) of type 2 diabetes were reported. Comparing the highest tertile to the lowest tertile of intake, the overall amount of Okinawan vegetables consumed was not associated with risk of type 2 diabetes in men (OR 1.22; 95% confidence interval [CI], 0.74-2.01, P-trend = 0.53) or in women (OR 0.96; 95% CI, 0.57-1.62, P-trend = 0.89). The consumption of seven specific kinds of Okinawan vegetables was also not associated with the risk of type 2 diabetes.
The consumption of total Okinawan vegetables was not associated with the risk of type 2 diabetes.
一些冲绳蔬菜已被报道具有抗糖尿病活性；然而，尚无前瞻性队列研究阐明食用冲绳蔬菜是否与 2 型糖尿病风险相关。本研究旨在通过在日本进行的一项大规模、基于人群的前瞻性研究，确定食用冲绳蔬菜与 2 型糖尿病风险之间的关联。
我们检查了 10732 名年龄在 45-74 岁、居住在冲绳的参与者（4714 名男性和 6018 名女性）。要求参与者回答一份 147 项食物频率问卷。我们计算了总的冲绳蔬菜摄入量和七种特定冲绳蔬菜的摄入量。通过多变量逻辑回归分析估计了 5 年随访期间报告的 2 型糖尿病的比值比（OR）。
在 5 年期间，报告了 216 例新的 2 型糖尿病病例（123 名男性和 93 名女性）。与摄入量最低三分位相比，男性（OR 1.22；95%置信区间 [CI]，0.74-2.01，P 趋势=0.53）或女性（OR 0.96；95%CI，0.57-1.62，P 趋势=0.89）的总冲绳蔬菜摄入量与 2 型糖尿病风险无关。七种特定冲绳蔬菜的摄入量也与 2 型糖尿病风险无关。
总的冲绳蔬菜摄入量与 2 型糖尿病风险无关。
