MOE, Key Laboratory of Cell Activities and Stress Adaptations, Lanzhou University, Lanzhou, 730000, Gansu Province, PR China; Department of Occupational and Environmental Health, School of Public Health, Lanzhou University, Lanzhou 730000, Gansu Province, PR China.
Department of Earth Resources and Environmental Engineering, Hanyang University, Seoul, 04763, South Korea.
Trends Plant Sci. 2019 Jul;24(7):611-624. doi: 10.1016/j.tplants.2019.04.001. Epub 2019 May 10.
Microalgae hold the promise of an inexpensive and sustainable source of biofuels. The existing microalgal cultivation technologies need significant improvement to outcompete other biofuel sources such as terrestrial plants. Application of 'algomics' approaches under different abiotic stress conditions could be an effective strategy for optimization of microalgal growth and production of high-quality biofuels. In this review, we discuss the roles of omics in understanding genome structure and biocomponents metabolism in various microalgal species to optimize sustainable biofuel production. Application of individual and integrated omics revealed that genes and metabolic pathways of microalgae have been altered under multiple stress conditions, resulting in an increase in biocomponents, providing a research platform for expansion of genetic engineering studies in microalgal strains.
微藻有望成为一种廉价且可持续的生物燃料来源。现有的微藻培养技术需要显著改进，才能与其他生物燃料来源（如陆地植物）竞争。在不同的非生物胁迫条件下应用“组学”方法可能是优化微藻生长和生产高质量生物燃料的有效策略。在这篇综述中，我们讨论了组学在理解各种微藻物种的基因组结构和生物成分代谢中的作用，以优化可持续的生物燃料生产。单独和综合组学的应用表明，微藻在多种胁迫条件下的基因和代谢途径已经发生了改变，导致生物成分的增加，为微藻菌株的遗传工程研究提供了一个扩展的研究平台。
