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本文引用的文献

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Lateral Hypothalamus as a Motivation-Cognition Interface in the Control of Feeding Behavior.外侧下丘脑作为进食行为控制中的动机-认知界面
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Neural substrates of fear-induced hypophagia in male and female rats.恐惧诱导的雄性和雌性大鼠摄食量减少的神经基础。
Brain Struct Funct. 2018 Jul;223(6):2925-2947. doi: 10.1007/s00429-018-1668-3. Epub 2018 Apr 27.
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Quantified Coexpression Analysis of Central Amygdala Subpopulations.量化中央杏仁核亚群的共表达分析。
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Ventromedial prefrontal cortex mediates sex differences in persistent cognitive drive for food.腹内侧前额叶皮层介导了持久的食物认知驱动的性别差异。
Sci Rep. 2018 Feb 2;8(1):2230. doi: 10.1038/s41598-018-20553-4.
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An Insula-Central Amygdala Circuit for Guiding Tastant-Reinforced Choice Behavior.岛叶-杏仁中央回路指导味觉强化选择行为。
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Accumbal D2 cells orchestrate innate risk-avoidance according to orexin signals.伏隔核 D2 细胞根据食欲素信号协调先天避险行为。
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Central amygdala circuits modulate food consumption through a positive-valence mechanism.中杏仁核回路通过正价值机制调节食物摄入。
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Lateral Hypothalamic GABAergic Neurons Encode Reward Predictions that Are Relayed to the Ventral Tegmental Area to Regulate Learning.外侧下丘脑 GABA 能神经元编码奖励预测,这些预测被传递到腹侧被盖区,以调节学习。
Curr Biol. 2017 Jul 24;27(14):2089-2100.e5. doi: 10.1016/j.cub.2017.06.024. Epub 2017 Jul 6.
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Homeostatic circuits selectively gate food cue responses in insular cortex.稳态回路选择性地控制岛叶皮质对食物线索的反应。
Nature. 2017 Jun 29;546(7660):611-616. doi: 10.1038/nature22375. Epub 2017 Jun 14.
10
Amygdala inputs to prefrontal cortex guide behavior amid conflicting cues of reward and punishment.在奖励与惩罚的冲突线索中,杏仁核向前额叶皮层的输入引导行为。
Nat Neurosci. 2017 Jun;20(6):824-835. doi: 10.1038/nn.4553. Epub 2017 Apr 24.

进食行为生存回路:预期与竞争。

Feeding Behavior Survival Circuit: Anticipation & Competition.

作者信息

Petrovich Gorica D

机构信息

Department of Psychology, Boston College, Chestnut Hill, MA,USA.

出版信息

Curr Opin Behav Sci. 2018 Dec;24:137-142. doi: 10.1016/j.cobeha.2018.09.007. Epub 2018 Sep 25.

DOI:10.1016/j.cobeha.2018.09.007
PMID:31086808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6510508/
Abstract

A decision to eat or not to eat can be beneficial or detrimental to an organism, depending on internal and external conditions. Because feeding is essential for survival, as it replenishes energy and nutrients, in safe environments, its expression is prioritized over other behaviors. Under threat, responding to danger is a higher priority for survival and feeding is paused even in hungry states. Thus, successful expression of feeding behavior requires adaptive control that utilizes cognitive processes to dynamically assess and update internal drives and environmental changes. Recently identified key circuit components, which are important in anticipatory responding based on food memories and predictions and in resolving feeding versus threat avoidance competition, will be discussed within a connectional schema.

摘要

进食或不进食的决定对生物体可能有益也可能有害,这取决于内部和外部条件。由于进食对生存至关重要,因为它能补充能量和营养,在安全的环境中,其表现比其他行为更受优先考虑。在受到威胁时,对危险做出反应对生存来说是更高的优先事项,即使处于饥饿状态,进食也会暂停。因此,进食行为的成功表现需要适应性控制,这种控制利用认知过程来动态评估和更新内部驱动力以及环境变化。本文将在一个连接模式中讨论最近确定的关键神经回路组件,这些组件在基于食物记忆和预测的预期反应以及解决进食与避免威胁的竞争中很重要。