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印度人口小肠长度的变异性及其与 2 型糖尿病和肥胖的相关性。

Variability of Length of Small Intestine in Indian Population and Its Correlation with Type 2 Diabetes Mellitus and Obesity.

机构信息

Poona Hospital & Research Centre, Pune, India.

出版信息

Obes Surg. 2019 Oct;29(10):3149-3153. doi: 10.1007/s11695-019-03921-5.

Abstract

PURPOSE

Previous studies have correlated small intestinal length with gender, age, weight, height and ethnic background. Some studies have reported a positive correlation of small intestinal length to body mass index (BMI). Some studies have shown that bypassing proximal small intestine can result in diabetes mellitus (DM) control. Present study was conducted to find correlation of small intestinal length with BMI and DM.

MATERIALS AND METHODS

Two hundred eighty-three patients aged between 18 and 60 years who underwent open or laparoscopic abdominal surgery were included. Height, weight, BMI, random blood sugar (RBS), HbA1c, etc. were noted. A standard 30-cm umbilical tape with 10 cm marking was used to measure the length of small intestine in laparotomy patients, whereas lap bowel graspers with marking of 10 cm on the shaft was used for laparoscopy patients. Statistical significance of normally distributed continuous variables was tested using independent sample t test. Spearman rank correlation was used to test association between two ranked variables.

RESULTS

The mean small intestinal length in Indian population was 777.1 cm with a standard deviation of 186.2 cm. Mean length of small intestine was significantly higher in patients who had HbA1c ≥ 6.5% and RBS levels ≥ 200 mg/dL. HbA1c and RBS showed significant but a weak positive correlation with length of small intestine. BMI did not show significant correlation with length of small intestine.

CONCLUSION

Small intestinal length had significant but a weak positive correlation in patients who had HbA1c ≥ 6.5% and RBS levels ≥ 200 mg/dL.

摘要

目的

先前的研究已经将小肠长度与性别、年龄、体重、身高和种族背景相关联。一些研究报告了小肠长度与体重指数(BMI)之间的正相关关系。一些研究表明,绕过近端小肠可以控制糖尿病(DM)。本研究旨在探讨小肠长度与 BMI 和 DM 的相关性。

材料和方法

纳入了 283 名年龄在 18 至 60 岁之间接受开腹或腹腔镜腹部手术的患者。记录了身高、体重、BMI、随机血糖(RBS)、HbA1c 等。在剖腹手术患者中使用标准的 30 厘米脐带,带有 10 厘米的标记来测量小肠长度,而在腹腔镜手术患者中使用带有 10 厘米标记的腹腔镜肠夹来测量小肠长度。使用独立样本 t 检验测试正态分布连续变量的统计学意义。使用 Spearman 秩相关检验测试两个等级变量之间的关联。

结果

印度人群的小肠平均长度为 777.1 厘米,标准差为 186.2 厘米。HbA1c≥6.5%和 RBS 水平≥200mg/dL 的患者小肠长度明显较高。HbA1c 和 RBS 与小肠长度呈显著但较弱的正相关。BMI 与小肠长度无显著相关性。

结论

HbA1c≥6.5%和 RBS 水平≥200mg/dL 的患者小肠长度与 HbA1c 和 RBS 呈显著但较弱的正相关。

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