Institute of Medical Physics, University of Sydney, Physics Road A28, Sydney, NSW, 2006, Australia.
School of Mathematical and Physical Sciences, University of Newcastle, Newcastle, NSW, 2300, Australia.
Med Phys. 2019 Jul;46(7):3298-3305. doi: 10.1002/mp.13591. Epub 2019 Jun 11.
Dosimetry of ionizing radiation in the presence of strong magnetic fields is gaining increased relevance in light of advances for MRI-guided radiation therapy. While the impact of strong magnetic fields on the overall response of ionization chambers has been simulated and measured before, this work investigates the local impact of the magnetic field on dose response in an ion chamber. High-resolution 1D and 2D response maps have been created for two small clinical thimble ionization chambers, the PinPoint chambers 31006 and 31014 (Physikalisch Technische Werkstaetten Freiburg, Germany).
Working on the Imaging and Medical Beam Line of the Australian Synchrotron an intense kilovoltage radiation beam with very low divergence, collimated to 0.1 mm was used to scan the chambers by moving them on a 2D motion platform. Measured current and beam position were correlated to create the response maps. Small neodymium magnets were used to create a field of about 0.25 T. Chamber axis, magnetic field, and beam direction were perpendicular to each other. Measurements were performed with both orientations of the magnetic field as well as without it. Chamber biases of 5 and 250 V in both polarities were used.
The local distribution of the response of small thimble-type ionization chambers was found to be impacted by a magnetic field. Depending on the orientation of the magnetic field, the chamber response near the stem was either enhanced or reduced with the response near the tip behaving the opposite way. Local changes were in the order of up to 40% compared to measurements without the magnetic field present. Bending of the central electrode was observed for the chamber with the steel electrode. The size of the volume of reduced collection near the guard electrode was impacted by the magnetic field. As the here investigated beam and field parameters differ from those of clinical systems, quantitatively different results would be expected for the latter. However, the gyroradii encountered here were similar to those of a 6-7 MV MRI linac with a 1.5 T magnet.
Magnetic fields impact the performance of ionization chambers also on a local level. For practical measurements this might mean a change in the effective point of measurement, in addition to any global corrections. Further knowledge about the local response will help in selecting or constructing optimized chambers for use in magnetic fields.
随着 MRI 引导放疗的发展,强磁场下的电离辐射剂量学变得越来越重要。虽然之前已经模拟和测量了强磁场对整个电离室响应的影响,但这项工作研究了磁场对电离室剂量响应的局部影响。为两个小型临床指状电离室,即 PinPoint chambers 31006 和 31014(德国弗赖堡物理技术研究所),创建了高分辨率的 1D 和 2D 响应图。
在澳大利亚同步加速器的成像和医疗束线上,使用具有极低发散度的强千伏辐射束,通过在二维运动平台上移动电离室来扫描。测量电流和束位置以创建响应图。使用小型钕磁铁产生约 0.25 T 的磁场。电离室轴、磁场和束方向彼此垂直。在有和没有磁场的两种情况下都进行了测量。使用 5 和 250 V 的两种极性的偏置电压。
发现小指状电离室的局部响应分布受到磁场的影响。根据磁场的方向,靠近柄部的腔室响应增强或减小,而靠近尖端的腔室响应则相反。与没有磁场存在时的测量结果相比,局部变化高达 40%。观察到带有钢电极的腔室的中心电极弯曲。受磁场影响,靠近保护电极的收集体积减小。由于这里研究的束和场参数与临床系统不同,预计后者会得到定量不同的结果。然而,这里遇到的回旋半径与具有 1.5 T 磁铁的 6-7 MV MRI 直线加速器相似。
磁场也会对电离室的性能产生局部影响。对于实际测量,除了任何全局校正之外,这可能意味着有效测量点的变化。进一步了解局部响应将有助于选择或构建用于磁场的优化腔室。