Wang Da-Peng, Zhang Xian, Yan Chang-Zhou
Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China.
University of Chinese Academy of Sciences, Beijing 100049, China.
Huan Jing Ke Xue. 2019 Mar 8;40(3):1347-1352. doi: 10.13227/j.hjkx.201804094.
Acetyl metabolites are the major metabolites of sulfonamides. In order to investigate the removal mechanism of four commonly used sulfonamides and their metabolites in wastewater treatment plants, sulfonamides and their corresponding acetyl metabolites in wastewater and sludge in a wastewater treatment plant equipped with A/O in Xiamen City were sampled. Sample selection was based on the hydraulic retention time. Solid phase extraction followed by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS) was applied to analyze the target compounds. Results showed that six out of eight of the target compounds were detected in the wastewater, while five were detected in the sludge. Based on the removal efficiencies overall and of the different compartments, the concentration of sulfamethazine was almost unchanged during wastewater treatment plant (WWTP) processes, the other sulfonamides were removed with different removal efficiencies. Removal efficiencies varied for every compartment. The potential removal pathways were analyzed based on the mass balance of the target compounds. The removal pathway of sulfamethazine was sludge adsorption, while the potential removal mechanism of sulfamerazine, sulfadiazine, and sulfamethoxazole was biodegradation.
乙酰代谢物是磺胺类药物的主要代谢产物。为了研究四种常用磺胺类药物及其代谢产物在污水处理厂中的去除机制，对厦门市某采用A/O工艺的污水处理厂的废水和污泥中的磺胺类药物及其相应的乙酰代谢物进行了采样。样本选取基于水力停留时间。采用固相萃取结合高效液相色谱串联质谱法（HPLC-MS/MS）分析目标化合物。结果表明，在废水中检测到了8种目标化合物中的6种，在污泥中检测到了5种。根据总体及不同处理单元的去除效率，磺胺二甲嘧啶在污水处理厂处理过程中的浓度几乎不变，其他磺胺类药物的去除效率各不相同。每个处理单元的去除效率也有所不同。基于目标化合物的质量平衡分析了潜在的去除途径。磺胺二甲嘧啶的去除途径是污泥吸附，而磺胺甲嘧啶、磺胺嘧啶和磺胺甲恶唑的潜在去除机制是生物降解。
