Ramos-Niembro F, Alarcon-Segovia D
J Rheumatol. 1978 Winter;5(4):433-40.
Three families are reported in which one member had MCTD and another member had either MCTD or systemic lupus erythematosus (SLE). In one family both mother and daughter probably had MCTD. The daughter, however, had prominent SLE features and kidney involvement. In another family, the mother had MCTD and the daughter had SLE; while in a third family one sister had MCTD and the other had SLE with prominent arthritis but negative anti-ribonucleoprotein (RNP) antibodies.
据报道，有三个家庭，其中一个成员患有混合性结缔组织病（MCTD），另一个成员患有MCTD或系统性红斑狼疮（SLE）。在一个家庭中，母亲和女儿可能都患有MCTD。然而，女儿有明显的SLE特征和肾脏受累。在另一个家庭中，母亲患有MCTD，女儿患有SLE；而在第三个家庭中，一个姐妹患有MCTD，另一个患有SLE且有关节炎突出但抗核糖核蛋白（RNP）抗体阴性。
