Kaufman R L, Kitridou R C
J Rheumatol. 1982 Jul-Aug;9(4):549-55.
The risk of pregnancy was evaluated in 31 patients with mixed connective tissue disease (MCTD), 31 patients with systemic lupus erythematosus (SLE) and 51 controls. The fertility rates in MCTD and SLE were unaltered by disease; however, parity was decreased and fetal wastage was increased both before and even more so after onset. It is our observation that pregnancy carries the same risks in MCTD as it does in SLE.
对31例混合性结缔组织病(MCTD)患者、31例系统性红斑狼疮(SLE)患者和51名对照者的妊娠风险进行了评估。MCTD和SLE患者的生育率并未因疾病而改变;然而,发病前和发病后,产次均有所下降,胎儿丢失率增加,且发病后更为明显。我们观察到,MCTD患者妊娠所面临的风险与SLE患者相同。