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Risks of all-cause and suicide mortality in mental disorders: a meta-review.精神障碍患者全因和自杀死亡率的风险:荟萃分析综述。
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Vitamin D supplementation for depressive symptoms: a systematic review and meta-analysis of randomized controlled trials.补充维生素D治疗抑郁症状:一项随机对照试验的系统评价和荟萃分析
Psychosom Med. 2014 Apr;76(3):190-6. doi: 10.1097/PSY.0000000000000044.
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Vitamin D hormone regulates serotonin synthesis. Part 1: relevance for autism.维生素D激素调节血清素的合成。第一部分:与自闭症的相关性。
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The association between low vitamin D and depressive disorders.维生素 D 水平低与抑郁障碍之间的关联。
Mol Psychiatry. 2014 Apr;19(4):444-51. doi: 10.1038/mp.2013.36. Epub 2013 Apr 9.
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Vitamin D deficiency and depression in adults: systematic review and meta-analysis.成人维生素 D 缺乏与抑郁:系统评价和荟萃分析。
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Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease.维生素 D,对大脑发育、成人大脑功能的影响,以及维生素 D 水平低与神经精神疾病之间的联系。
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Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1.维生素 D 通过靶向 MAPK 磷酸酶-1 抑制单核细胞/巨噬细胞促炎细胞因子的产生。
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办公室职员抑郁症状与可改变的生活方式风险因素之间的关系

The Relationship between Depressive Symptoms and Modifiable Lifestyle Risk Factors in Office Workers.

作者信息

Jin Youngyun, Ha Changduk, Hong Hyeryun, Kang Hyunsik

机构信息

College of Sport Science, Sungkyunkwan University, Suwon, Korea.

出版信息

J Obes Metab Syndr. 2017 Mar;26(1):52-60. doi: 10.7570/jomes.2017.26.1.52. Epub 2017 Mar 30.

DOI:10.7570/jomes.2017.26.1.52
PMID:31089494
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6484929/
Abstract

BACKGROUND

This study investigated the relationship between depressive symptoms and physical fitness, obesity indices, and vitamin D status in office workers.

METHODS

The subjects were 514 adults with more 30 years of experience as office workers in the city of Seoul. Lifestyle risk factors, obesity indices, physical fitness, and serum vitamin D levels were assessed with a standardized protocol. The Beck Depression Inventory (BDI) was used to assess depression status. Vitamin D status was assessed by measuring serum 25-hydroxyvitamin D concentrations. Based on the BDI scores, participants were classified into no depression (ND, BDI ≤9), mild depression (MiD, 10≤BDI≤15), and moderate depression (MoD, 16≤BDI≤23) groups.

RESULTS

Compared with the high cardiorespriatory fitness group, the low cardiorespiratory fitness (men OR=2.618, women OR=1.596) an middle cardiorespiratory fitness group (men OR=1.256, women OR=1.110) had significantly higher odds ratio for having depressive symptoms, even after adjustment for age, hypertension, diabetes, hyperlipidemia, cardiovascular disease, alcohol intake, smoking, body mass index (BMI), percent body fat (%BF), and waist circumference (WC). Compared with the insufficient or deficient vitamin D group, the sufficient vitamin D group had significantly lower odds ratios for having depressive symptoms (men OR=0.121, women OR=0.114), even after adjustment for age, hypertension, diabetes, hyperlipidemia, cardiovascular disease, alcohol intake, smoking, BMI, %BF, and WC.

CONCLUSION

Vitamin D supplementation and outdoor activities should be key components of a lifestyle intervention against office workers' depression.

摘要

背景

本研究调查了上班族抑郁症状与身体素质、肥胖指数及维生素D状况之间的关系。

方法

研究对象为514名在首尔市有超过30年上班族经历的成年人。采用标准化方案评估生活方式风险因素、肥胖指数、身体素质和血清维生素D水平。使用贝克抑郁量表(BDI)评估抑郁状况。通过测量血清25-羟维生素D浓度评估维生素D状况。根据BDI评分,参与者被分为无抑郁(ND,BDI≤9)、轻度抑郁(MiD,10≤BDI≤15)和中度抑郁(MoD,16≤BDI≤23)组。

结果

与高心肺适能组相比,低心肺适能组(男性OR=2.618,女性OR=1.596)和中心肺适能组(男性OR=1.256,女性OR=1.110)出现抑郁症状的比值比显著更高,即使在调整了年龄、高血压、糖尿病、高脂血症、心血管疾病、酒精摄入、吸烟、体重指数(BMI)、体脂百分比(%BF)和腰围(WC)之后。与维生素D不足或缺乏组相比,维生素D充足组出现抑郁症状的比值比显著更低(男性OR=0.121,女性OR=0.114),即使在调整了年龄、高血压、糖尿病、高脂血症、心血管疾病、酒精摄入、吸烟、BMI、%BF和WC之后。

结论

补充维生素D和进行户外活动应成为针对上班族抑郁的生活方式干预的关键组成部分。