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口腔黏膜的非肿瘤性疾病和病变:当代概述。

Nonneoplastic diseases and disorders of the oral mucosa: A contemporary overview.

机构信息

College of Medicine and Dentistry, James Cook University, Cairns, Australia.

Metro South Oral Health, Queensland Health, Australia.

出版信息

Periodontol 2000. 2019 Jun;80(1):7-11. doi: 10.1111/prd.12272.

DOI:10.1111/prd.12272
PMID:31090140
Abstract

Oral mucosal diseases encompass a diverse array of conditions and disorders arising from malignant, potentially malignant, and nonneoplastic processes. Considerable attention has been paid to the former in recent years, much less to the wide range of nonneoplastic disease processes, which constitute a sizeable proportion of the oral disease burden globally. Many nonneoplastic disease processes of the oral mucosa significantly affect the patient's quality of life. Fortunately, timely identification and intervention can reduce the associated morbidity and, sometimes, mortality. As such, it is of utmost importance that dentists are familiar with early identification and management of this wide range of oral mucosal diseases. This volume of Periodontology 2000 provides a comprehensive contemporary review of such diseases and disorders through 15 chapters. We cover all relevant disease categories: developmental anomalies, infections, white and red lesions, vesiculo-bullous diseases, oral dermatoses, oral ulcerative conditions, dysplastic lesions, and mucosal diseases as manifestations of systemic disease or oral lesions as a part of systemic diseases. Each chapter discusses epidemiology, etiopathogenesis, clinical features, diagnosis, and management. Controversies and many significant gaps in knowledge are exposed, with suggestions for research to address limitations in current understandings. We take a look at the 2017 classification of the periodontal diseases and discuss the importance of close liaison between the specialties of oral medicine and of periodontology in the management of the many oral diseases, apart from the common forms primarily related to oral biofilm, affecting the gingivae and other parts of the periodontium.

摘要

口腔黏膜病涵盖了一系列由恶性、潜在恶性和非肿瘤过程引起的病症。近年来,人们对前者给予了相当多的关注,而对范围广泛的非肿瘤性疾病过程则关注较少,这些疾病过程构成了全球口腔疾病负担的相当大一部分。许多口腔黏膜的非肿瘤性疾病过程会显著影响患者的生活质量。幸运的是,及时的识别和干预可以降低相关的发病率,有时甚至可以降低死亡率。因此,牙医熟悉这一系列广泛的口腔黏膜疾病的早期识别和管理至关重要。《牙周病学 2000》的这一卷通过 15 章全面回顾了这些疾病和障碍。我们涵盖了所有相关的疾病类别:发育异常、感染、白色和红色病变、水疱-大疱性疾病、口腔皮肤病、口腔溃疡性疾病、发育不良病变以及作为全身性疾病表现或作为全身性疾病一部分的黏膜疾病。每一章都讨论了流行病学、病因发病机制、临床特征、诊断和治疗。我们揭示了争议和许多知识上的重大差距,并提出了研究建议,以解决目前理解的局限性。我们研究了 2017 年牙周病的分类,并讨论了口腔医学和牙周病学专业之间密切联系的重要性,除了主要与口腔生物膜有关的常见形式外,这些联系在管理影响牙龈和牙周组织其他部分的许多口腔疾病中非常重要。

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Nonneoplastic diseases and disorders of the oral mucosa: A contemporary overview.口腔黏膜的非肿瘤性疾病和病变:当代概述。
Periodontol 2000. 2019 Jun;80(1):7-11. doi: 10.1111/prd.12272.
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Genetic and developmental disorders of the oral mucosa: Epidemiology; molecular mechanisms; diagnostic criteria; management.口腔黏膜的遗传和发育障碍:流行病学;分子机制;诊断标准;治疗。
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Oral mucosal diseases: the inflammatory dermatoses.口腔黏膜疾病:炎症性皮肤病。
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