Department of Kinesiology & Public Health, California Polytechnic State University, 1 Grand Ave, San Luis Obispo, CA 93407, USA.
Division of Epidemiology, University of California at Berkeley School of Public Health, 2121 Berkeley Way #5302, Berkeley, CA 94720-7360, USA.
Nutrients. 2019 May 14;11(5):1071. doi: 10.3390/nu11051071.
A behavioral lifestyle intervention with partial meal replacement reduced excess gestational weight gain in ethnically diverse women with overweight/obesity, but the effects on micronutrient intake remained unknown. A secondary analysis of a randomized, controlled trial tested whether the intervention improved micronutrient intake relative to usual care. Pregnant women ( = 211; 30.5 years of age, body mass index, BMI, of 32.0 kg/m) were enrolled and randomized within site and ethnicity (40% were Hispanic) into intervention ( = 102) or usual care ( = 109) groups. Two 24 h dietary recalls were conducted on random days at study entry and late pregnancy (35⁻36 weeks gestation). Nutrient adequacy was defined using the Estimated Average Requirement cut-point method. At study entry and including prenatal vitamins, ≥90% of participants reported inadequate intake of vitamins D and E and iron; 40⁻50% reported inadequate intake of calcium, protein, vitamins A, C, B, folate, magnesium, and zinc. From study entry to late pregnancy, the behavioral intervention with partial meal replacement increased the overall intake of vitamins A, E, and D and copper and reduced the odds of inadequate intake of calcium (odds ratio (OR) = 0.37 (0.18, 0.76)), vitamins A (OR = 0.39 (0.21, 0.72)) and E (OR = 0.17 (0.06, 0.48)), and magnesium (OR = 0.36 (0.20, 0.65)). A behavioral intervention with partial meal replacement during pregnancy improved the intake of several micronutrients in Hispanic and non-Hispanic women with overweight/obesity.
一种行为生活方式干预措施，辅以部分代餐，可减少超重/肥胖的不同族裔孕妇的妊娠体重过度增加，但对微量营养素摄入的影响尚不清楚。一项随机对照试验的二次分析检验了该干预措施是否相对于常规护理改善了微量营养素的摄入。将怀孕的女性（n=211；年龄 30.5 岁，体重指数为 32.0kg/m²）按照地点和种族（40%为西班牙裔）进行分层随机分组，分为干预组（n=102）和常规护理组（n=109）。在研究开始时和妊娠晚期（35-36 周妊娠）的随机日进行两次 24 小时膳食回忆。使用估计平均需要量（EAR）切点法定义营养素充足性。在研究开始时，包括产前维生素在内，≥90%的参与者报告维生素 D 和 E 以及铁摄入不足；40-50%的参与者报告钙、蛋白质、维生素 A、C、B、叶酸、镁和锌摄入不足。从研究开始到妊娠晚期，部分代餐的行为干预增加了维生素 A、E 和 D 以及铜的总体摄入量，并降低了钙摄入不足的几率（比值比（OR）=0.37（0.18，0.76）），维生素 A（OR=0.39（0.21，0.72））和 E（OR=0.17（0.06，0.48）），以及镁（OR=0.36（0.20，0.65））。妊娠期间，部分代餐的行为干预改善了超重/肥胖的西班牙裔和非西班牙裔女性的几种微量营养素摄入。
