Whiting Penny, Davenport Clare
1NIHR CHLARC West, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
2Bristol Medical School, University of Bristol, Bristol, UK.
Diagn Progn Res. 2018 Feb 1;2:2. doi: 10.1186/s41512-017-0023-0. eCollection 2018.
Presenting results of diagnostic test accuracy research so that it is accessible to users is challenging. Commonly used accuracy measures (e.g. sensitivity and specificity) are poorly understood by health professionals and the public. Evidence suggests that presenting probabilities as natural frequencies rather than percentages facilitates understanding. We present a test consequence graphic to display results based on natural frequencies and test consequences.
The graphic was developed as part of a project to develop guidance for writing plain language summaries for Cochrane diagnostic test accuracy (DTA) reviews. Using a mixed methods approach (focus groups, user testing, web-based surveys, public engagement and piloting), the graphic emerged as a clear preference out of a range of methods for presenting probabilistic information (text only, numbers embedded in text, annotated graphic) across patient representatives, media representatives and health professionals. The structure of the graphic was refined during the research process.
The test consequence graphic displays the results of diagnostic test accuracy study or review as natural frequencies based on a hypothetical cohort of 1000 patients receiving the test.
The test consequence graphic provides a tool to help researchers communicate the results of diagnostic research in a simple, easy to access format and encourage meaningful application of research findings to practice. Key to this is linking estimates of test accuracy to potential downstream consequences of testing.
展示诊断测试准确性研究结果以便用户能够理解具有挑战性。卫生专业人员和公众对常用的准确性指标(如敏感性和特异性)了解甚少。有证据表明,将概率以自然频率而非百分比的形式呈现有助于理解。我们展示一种测试结果图表,用于基于自然频率和测试结果来呈现结果。
该图表是为制定Cochrane诊断测试准确性(DTA)综述的通俗易懂总结撰写指南的项目的一部分而开发的。采用混合方法(焦点小组、用户测试、网络调查、公众参与和试点),在患者代表、媒体代表和卫生专业人员提出的一系列呈现概率信息的方法(仅文本、嵌入文本的数字、带注释的图表)中,该图表成为明显的首选。图表的结构在研究过程中得到了完善。
测试结果图表将诊断测试准确性研究或综述的结果呈现为基于接受该测试的1000名患者的假设队列的自然频率。
测试结果图表提供了一种工具,帮助研究人员以简单、易于理解的格式交流诊断研究结果,并鼓励将研究结果有意义地应用于实践。关键在于将测试准确性的估计与测试潜在的下游后果联系起来。