Mitchell Stephanie, Gomes Allison, Zelig Rena, Parker Anna
School of Health Professions, Department of Clinical and Preventive Nutrition Sciences at Rutgers University, Newark, NJ.
Curr Dev Nutr. 2019 Mar 27;3(5):nzz020. doi: 10.1093/cdn/nzz020. eCollection 2019 May.
Adequate folate intake during the female reproductive years plays a vital role in fetal neurodevelopment. To address this public health concern, the FDA required enriched cereal grains to be fortified with folic acid. A positive outcome of fortification with folic acid was a reduction in the number of pregnancies affected by neural tube defects (NTDs). However, there are individuals unable to consume these enriched grains, such as those with a gluten allergy or intolerance. The need for folic acid fortification across all grains, those with and without gluten, should be considered in an effort to provide equivalent folic acid to all and further promote public health efforts aimed at decreasing the incidence of NTDs.
女性生殖年龄段摄入充足的叶酸对胎儿神经发育起着至关重要的作用。为解决这一公共卫生问题，美国食品药品监督管理局（FDA）要求强化谷物要添加叶酸。添加叶酸的一个积极成果是受神经管缺陷（NTDs）影响的妊娠数量减少。然而，有一些人无法食用这些强化谷物，比如患有麸质过敏或不耐受的人。应该考虑对所有谷物（无论有无麸质）进行叶酸强化，以便为所有人提供等量的叶酸，并进一步推动旨在降低神经管缺陷发病率的公共卫生工作。
