Pan Jeffrey Y
Integrated Science and Technology (iSAT) Discovery, Specialized Research in Chaotic Systems (SPaRCS), AbbVie, 1 North Waukegan Road, North Chicago, Illinois 60064-6212, United States.
ACS Med Chem Lett. 2019 Apr 25;10(5):703-707. doi: 10.1021/acsmedchemlett.9b00096. eCollection 2019 May 9.
Automation of chemistry at a pharmaceutical company commonly entails bringing commercial solutions in-house, reproducing manual processes with a robot, or integrating multiple instruments to eliminate human intervention. A strategy of industrializing proven approaches, while financially justifiable, however, does not encourage innovation. On the other hand, trying to automate unproven or difficult processes may seem to be risky but can actually accelerate the adoption, modification, or rejection of novel technologies. Having chemists and engineers work together to develop automation that accelerates the development and evaluation of innovative concepts is one blueprint for delivering a competitive advantage to an organization.
制药公司的化学自动化通常需要引入内部商业解决方案、用机器人重现手动流程或整合多种仪器以消除人为干预。然而，将经过验证的方法工业化的策略虽然在财务上合理，但并不鼓励创新。另一方面，尝试自动化未经证实或困难的流程看似有风险，但实际上可以加速新技术的采用、改进或摒弃。让化学家和工程师共同努力开发能加速创新概念的开发和评估的自动化技术，是为组织带来竞争优势的一个蓝图。
