Buskirk Elsworth R, Thompson Ronald H, Whedon G Donald
J Appl Physiol (1985). 1963 May 1;18(3):603-612. doi: 10.1152/jappl.1963.18.3.603.
Eight healthy young men (ages 19–35), four older men (ages 38–42), three obese subjects (two women and one man, ages 20–34) were individually exposed on one or more occasions to 10 C (50 F) air in the Metabolic Chamber for periods of 2–4 hr. A minimal amount of clothing was worn: the males wore shorts and the females wore halters and shorts. Air movement was routinely less than 50 ft/min and relative humidity 50% or less. Body fatness among the subjects ranged from 13 to 45% of body weight. The metabolic response to cold determined from Vo2 and Vco2 was significantly and inversely related to per cent body fat according to the regression equation: kcal/(m2·hr) = 65.2 – 0.520 (% fat) ± 0.115. Total body insulation after 2 hr of exposure was significantly and directly related to per cent body fat and inversely related to the metabolic response. Despite these significant relationships, wide individual differences were observed in the metabolic response to cold between pairs of subjects of like age, previous history of cold exposure, and body fatness.
八名健康青年男性（年龄19 - 35岁）、四名老年男性（年龄38 - 42岁）、三名肥胖受试者（两名女性和一名男性，年龄20 - 34岁）分别在代谢室中一次或多次暴露于10摄氏度（50华氏度）的空气中，持续2 - 4小时。穿着极少的衣物：男性穿短裤，女性穿背心和短裤。空气流动通常小于50英尺/分钟，相对湿度为50%或更低。受试者的体脂率在体重的13%至45%之间。根据回归方程：千卡/（平方米·小时）= 65.2 - 0.520（%脂肪）± 0.115，由耗氧量（Vo2）和二氧化碳排出量（Vco2）确定的对寒冷的代谢反应与体脂百分比呈显著负相关。暴露2小时后的全身隔热与体脂百分比呈显著正相关，与代谢反应呈负相关。尽管存在这些显著关系，但在年龄、既往寒冷暴露史和体脂率相似的受试者对之间，对寒冷的代谢反应仍存在很大的个体差异。
