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Binocular amblyopia treatment with contrast-rebalanced movies.

作者信息

Birch Eileen E, Jost Reed M, De La Cruz Angie, Kelly Krista R, Beauchamp Cynthia L, Dao Lori, Stager David, Leffler Joel N

机构信息

Retina Foundation of the Southwest, Dallas, Texas; UT Southwestern Medical Center, Dallas, Texas.

Retina Foundation of the Southwest, Dallas, Texas.

出版信息

J AAPOS. 2019 Jun;23(3):160.e1-160.e5. doi: 10.1016/j.jaapos.2019.02.007. Epub 2019 May 16.


DOI:10.1016/j.jaapos.2019.02.007
PMID:31103562
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6698207/
Abstract

BACKGROUND: Binocular amblyopia treatments promote visual acuity recovery and binocularity by rebalancing the signal strength of dichoptic images. Most require active participation by the amblyopic child to play a game or perform a repetitive visual task. The purpose of this study was to investigate a passive form of binocular treatment with contrast-rebalanced dichoptic movies. METHODS: A total of 27 amblyopic children, 4-10 years of age, wore polarized glasses to watch 6 contrast-rebalanced dichoptic movies on a passive 3D display during a 2-week period. Amblyopic eye contrast was 100%; fellow eye contrast was initially set to a lower level (20%-60%), which allowed the child to overcome suppression and use binocular vision. Fellow eye contrast was incremented by 10% for each subsequent movie. Best-corrected visual acuity, random dot stereoacuity, and interocular suppression were measured at baseline and at 2 weeks. RESULTS: Amblyopic eye best-corrected visual acuity improved from 0.57 ± 0.22 at baseline to 0.42 ± 0.23 logMAR (t = 8.09; P < 0.0001; 95% CI for improvement, 0.11-0.19 logMAR). Children aged 3-6 years had more improvement (0.21 ± 0.11 logMAR) than children aged 7-10 years (0.11 ± 0.06 logMAR; t = 3.05; P = 0.005). Children with severe amblyopia (≥0.7 logMAR) at baseline experienced greater improvement (0.24 ± 0.12 logMAR) than children with moderate amblyopia at baseline (0.12 ± 0.06 logMAR; t = 3.49; P = 0.002). CONCLUSIONS: In this cohort, passive viewing of contrast-rebalanced dichoptic movies effectively improved visual acuity in amblyopic subjects. The degree of improvement observed was similar to that previously reported for 2 weeks of binocular games treatment and with 3-4 months of occlusion therapy.

摘要

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Binocular amblyopia treatment with contrast-rebalanced movies.

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引用本文的文献

[1]
Dichoptic Visual Search at Varied Fellow Eye Contrasts and Visual Function Deficits in Amblyopia.

Invest Ophthalmol Vis Sci. 2025-7-1

[2]
Comparison of a novel gamified binocular therapy and standard monocular patching therapy in treating unilateral amblyopia in young children: a prospective, multicenter, randomized controlled trial.

Trials. 2025-6-20

[3]
Ocular Dominance Plasticity: A Mini-Review.

Eye Brain. 2025-6-10

[4]
Assessing Previous Strategies and Presenting a Novel Smart Glasses to Enhance Adherence to Amblyopia Therapy in Children.

Patient Prefer Adherence. 2025-5-21

[5]
Successful persistent strabismic amblyopia treatment using active therapy as an adjuvant to occlusion.

J Optom. 2025-5-21

[6]
Binocular Approaches in Amblyopia Treatment Based on Dichoptic Stimulation.

Turk J Ophthalmol. 2025-6-25

[7]
Baseline and outcome stereoacuity of children with anisometropic amblyopia undergoing dichoptic amblyopia treatment.

J AAPOS. 2025-2

[8]
Transformative Gamified Binocular Therapy for Unilateral Amblyopia in Young Children: Pilot Prospective Efficacy and Safety Study.

JMIR Serious Games. 2025-1-16

[9]
Evaluating Eye Tracking During Dichoptic Video Viewing With Varied Fellow Eye Contrasts in Amblyopia.

Invest Ophthalmol Vis Sci. 2024-12-2

[10]
Patch-free streaming contrast-rebalanced dichoptic cartoons versus patching for treatment of amblyopia in children aged 3 to 5 years: a pilot, randomized clinical trial.

J AAPOS. 2024-10

本文引用的文献

[1]
Self-perception in Children Aged 3 to 7 Years With Amblyopia and Its Association With Deficits in Vision and Fine Motor Skills.

JAMA Ophthalmol. 2019-5-1

[2]
Self-perception of School-aged Children With Amblyopia and Its Association With Reading Speed and Motor Skills.

JAMA Ophthalmol. 2019-2-1

[3]
A Randomized Trial of Binocular Dig Rush Game Treatment for Amblyopia in Children Aged 7 to 12 Years.

Ophthalmology. 2018-10-22

[4]
Fixation instability during binocular viewing in anisometropic and strabismic children.

Exp Eye Res. 2018-7-10

[5]
An action video game for the treatment of amblyopia in children: A feasibility study.

Vision Res. 2018-7

[6]
The Amblyopia Treatment Studies: Implications for Clinical Practice.

Adv Ophthalmol Optom. 2016-8

[7]
Prescribed computer games in addition to occlusion versus standard occlusion treatment for childhood amblyopia: a pilot randomised controlled trial.

Pilot Feasibility Stud. 2015-6-11

[8]
Binocular iPad Game vs Patching for Treatment of Amblyopia in Children: A Randomized Clinical Trial.

JAMA Ophthalmol. 2016-12-1

[9]
Effect of a Binocular iPad Game vs Part-time Patching in Children Aged 5 to 12 Years With Amblyopia: A Randomized Clinical Trial.

JAMA Ophthalmol. 2016-12-1

[10]
Assessing Suppression in Amblyopic Children With a Dichoptic Eye Chart.

Invest Ophthalmol Vis Sci. 2016-10-1

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