Human Genetics Unit, Faculty of Medicine, University of Colombo, Sri Lanka.
Mol Genet Genomic Med. 2019 Jun;7(6):e744. doi: 10.1002/mgg3.744. Epub 2019 May 20.
The completion of the Human Genome Project in 2003 heralded in a new era marked by remarkable advances in biomedical research leading to the establishment of genomics-based translational medicine mainly in the developed world. However, the development of such advances has been hampered in most parts of the developing world due to scarcity of resources and trained personnel. Genetics and genomic medicine are currently in the process of being integrated into the Sri Lankan health care system. These developments have taken place mainly due to the heightened awareness and increasing demands made by the public for provision of genetic diagnostic and therapeutic services in clinical care. Due to the exorbitant costs incurred in the maintenance of these services and the dearth of adequately trained manpower, only a few centers in the country, mainly in Universities or private sector, are currently engaged in providing these services to the public. This article aims to provide an overview of the genetics and genomic medicine services in Sri Lanka from its early developments to the current state.
2003 年人类基因组计划的完成标志着一个新时代的到来，这个时代的生物医学研究取得了显著的进展，导致了基于基因组学的转化医学的建立，主要在发达国家。然而，由于资源和训练有素的人员的匮乏，大多数发展中国家的此类进展都受到了阻碍。遗传学和基因组医学目前正在被纳入斯里兰卡的医疗保健系统。这些发展主要是由于公众对在临床护理中提供遗传诊断和治疗服务的意识提高和需求增加所致。由于维持这些服务的高昂成本以及缺乏足够训练有素的人力，目前只有该国的少数几个中心，主要是在大学或私营部门，正在向公众提供这些服务。本文旨在概述斯里兰卡的遗传学和基因组医学服务，从早期发展到当前状况。
