Sirisena Nirmala D, Dissanayake Vajira H W
Human Genetics Unit, Faculty of Medicine, University of Colombo, Kynsey Road, Colombo 8, Sri Lanka.
J Community Genet. 2017 Oct;8(4):275-281. doi: 10.1007/s12687-017-0311-y. Epub 2017 Jul 11.
Although we are well into the second decade after the completion of the International Human Genome Project, genomic research has failed to fully represent the diverse ancestry of global populations. The resultant healthcare challenges faced by populations underrepresented in genomic research needs to be tackled by the global scientific community. In this paper, we address several major factors which have contributed to the existing health disparity and put forward a combination of scientific and political interventions needed to bring about a change that will ensure all global populations benefit equally from the advances made in genomic medicine and research.
尽管国际人类基因组计划完成后已顺利进入第二个十年,但基因组研究仍未能充分体现全球人群的多样血统。基因组研究中代表性不足的人群所面临的医疗保健挑战,需要全球科学界加以应对。在本文中,我们探讨了导致现有健康差距的几个主要因素,并提出了一系列科学和政治干预措施,以实现变革,确保所有全球人群都能平等受益于基因组医学和研究的进展。