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中国西南地区 2017 年携带新型金属β-内酰胺酶 5 的肺炎克雷伯菌 258 型序列类型

New Delhi Metallo-β-Lactamase 5-Producing Klebsiella pneumoniae Sequence Type 258, Southwest China, 2017.

出版信息

Emerg Infect Dis. 2019 Jun;25(6):1209-1213. doi: 10.3201/eid2506.181939.

DOI:10.3201/eid2506.181939
PMID:31107227
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6537745/
Abstract

We isolated a New Delhi metallo-β-lactamase 5 (NDM-5)-producing Klebsiella pneumoniae sequence type (ST) 258 strain in southwest China during 2017. The bla gene was acquired by horizontal plasmid transfer from NDM-5-producing Escherichia coli. We identified genomic characteristics in ST258 strains that differed from those of global K. pneumoniae carbapenemase-producing strains.

摘要

2017 年,我们在中国西南部分离到一株携带新型德里金属β-内酰胺酶 5(NDM-5)的肺炎克雷伯菌序列类型(ST)258 菌株。bla 基因通过水平质粒转移从产 NDM-5 的大肠杆菌获得。我们鉴定了 ST258 菌株的基因组特征,这些特征与全球产碳青霉烯酶的肺炎克雷伯菌菌株不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d136/6537745/59cd17c68131/18-1939-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d136/6537745/179896129a1b/18-1939-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d136/6537745/59cd17c68131/18-1939-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d136/6537745/179896129a1b/18-1939-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d136/6537745/59cd17c68131/18-1939-F2.jpg

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