Wu Qinqin, Zhang Fan, Li Ruicen, Li Wenyu, Gou Dan, Wang Lin
Health Management Center, West China Hospital, Sichuan University, Chengdu, China.
Department of Cardiology, West China Hospital, Sichuan University, No.37 Guoxue Road, Chengdu, 610041, Sichuan, China.
High Blood Press Cardiovasc Prev. 2022 Sep;29(5):417-428. doi: 10.1007/s40292-022-00528-3. Epub 2022 Jul 1.
This population-based cross-sectional study aimed to identify the best predictor of the 10-year cardiovascular (CV) high risk among old and new anthropometric indices.
We investigated 76,915 adults older than 18 years of age living in southwest China. Ten obesity indices were calculated. The 10-year cardiovascular disease (CVD) risk was estimated using the Framingham risk score. Receiver operating characteristic curve analysis was performed to assess the ability of the anthropometric index to predict the 10-year high risk of CVD events.
The waist-to-hip ratio (WHR) had the highest area under the curve (AUC) value (0.711; sensitivity: 62.22%, specificity: 42.73%) in men, while the body fat index (BAI) had the lowest AUC value (0.624, sensitivity: 49.07%, specificity: 54.84%). The waist-to-height ratio (WHtR) and the body roundness index (BRI) showed the highest AUC value (0.751, sensitivity: 39.24%, 39.83%, specificity: 75.68%, 68.59%) in women, while the BAI showed the lowest AUC value (0.671, sensitivity: 53.15%, specificity: 57.14%).
The WHR was the best anthropometric measure for assessing the 10-year high risk of CVD in men, while the WHtR and BRI were the best measures for women. In men, the WHR should be < 0.88, and in women, the WHtR should be < 0.502 or the BRI should be < 3.41.
这项基于人群的横断面研究旨在确定新旧人体测量指标中10年心血管(CV)高风险的最佳预测指标。
我们调查了居住在中国西南部的76915名18岁以上的成年人。计算了10种肥胖指数。使用弗雷明汉风险评分估算10年心血管疾病(CVD)风险。进行受试者工作特征曲线分析以评估人体测量指标预测10年CVD事件高风险的能力。
男性中腰臀比(WHR)的曲线下面积(AUC)值最高(0.711;敏感性:62.22%,特异性:42.73%),而体脂指数(BAI)的AUC值最低(0.624,敏感性:49.07%,特异性:54.84%)。女性中腰高比(WHtR)和身体圆润指数(BRI)的AUC值最高(0.751,敏感性:39.24%,39.83%,特异性:75.68%,68.59%),而BAI的AUC值最低(0.671,敏感性:53.15%,特异性:57.14%)。
WHR是评估男性10年CVD高风险的最佳人体测量指标,而WHtR和BRI是女性的最佳指标。男性中,WHR应<0.88,女性中,WHtR应<0.502或BRI应<3.41。