Division of Botany, Institute of Biology, University of Opole, Oleska 22, 45-052, Opole, Poland.
Department of Physiotherapy, Institute of Physiotherapy, Opole University of Technology, Prószkowska 76, 45-758, Opole, Poland.
J Ethnobiol Ethnomed. 2019 May 23;15(1):24. doi: 10.1186/s13002-019-0298-z.
Krummhübel (after 1945, Karpacz) in the Sudety Mountains (now SW Poland) was called "the village of pharmacists". At the end of the seventeenth century, there were 57 households, of which about 40 were inhabited by herbalists. Krummhübel herbalists were the first in the Sudety region who applied medicinal mixtures for the treatment of various diseases (using, among others, plants, oils, minerals and even viper venom) in contrast to previous herbalists who only indicated the use of individual plant species for specific diseases. Riesengebirge (in Polish Karkonosze) potions were sold in Austria, the Czech Republic, Poland and Russia, and some of them could even be purchased in Scandinavia and England. The purpose of this paper is an ethnopharmacological analysis of historical texts of herbalists from Krummhübel. Based on their recipes, we analysed the use reports of drugs. Recently, research on ethnobotany and ethnopharmacological analyses of historical materials or egodocuments related to formulations used in folk medicine have become an important source of acquiring knowledge about new medicines.
Based on 46 recipes of Krummhübel herbalists re-written by Reitzig (1943), we analysed the use reports of drugs which included plant taxa and other constituents such as animal formulations, fungi, inorganic and organic substances and minerals as well as tinctures (with alcohol/spirit) and elixirs (without alcohol/spirit). For each usage mentioned in the text, we recorded (i) the putative botanical identity of the taxon; (ii) the plant family or origin of other than the plant constituent; (iii) the reported plant part; (iv) the number of the recipe; (v) the name of the recipe; (vi) the vernacular name of ingredient; (vii) the described symptom, ailment or specific use; (viii) our modern (viz. biomedical) interpretation of the described symptom or ailment; (ix) the mode of administration; and (x) the category of use under which we filed the specific use. We also cross-checked the medicinal plants of Krummhübel herbalists with the species described in old manuscripts and regional surveys and compared their use with contemporary plant use.
The paper introduces the generated database comprising 348 use reports of 46 drugs based on 70 plant taxa and other constituents. Besides, we address patterns such as the frequent recommendation of Fabaceae herbs for respiratory system issue and gynaecology and Asteraceae for respiratory system and cardiovascular problems. Gastrointestinal use reports are based on Asphodelaceae, Burseraceae and Rosaceae species.
Remedies that lost importance over time as well as drugs used for diseases now controlled by conventional medicine may be interesting starting points for research on herbal medicine and drug discovery. It seems to be important to attempt to reproduce therapeutic mixtures from the preserved recipes of Krummhübel herbalists, which offers an opportunity to learn more about the real effects of the former medicines and their therapeutic activity. The obtained data can also be used to search for new drugs.
位于苏台德山脉(现波兰西南部)的克鲁姆洛夫(1945 年后称卡尔斯巴德)曾被称为“药剂师村”。在 17 世纪末,这里有 57 户人家,其中约有 40 户是草药师。克鲁姆洛夫的草药师是苏台德地区第一批应用药用混合物治疗各种疾病的人(除了使用植物、油、矿物质,甚至蝰蛇毒液外),与之前只指示使用特定植物物种治疗特定疾病的草药师不同。 Riesengebirge(波兰语中的喀尔巴阡山脉)的药水在奥地利、捷克共和国、波兰和俄罗斯销售,其中一些甚至可以在斯堪的纳维亚和英国购买。本文的目的是对来自克鲁姆洛夫的草药师的历史文本进行民族药理学分析。基于他们的配方,我们分析了药物的使用报告。最近,对民族植物学和与民间医学中使用的制剂相关的历史材料或自我报告的民族药理学分析已成为获取新药知识的重要来源。
基于赖茨格(Reitzig)于 1943 年重写的 46 个克鲁姆洛夫草药师的配方,我们分析了药物使用报告,其中包括植物类群和其他成分,如动物制剂、真菌、无机和有机物质以及矿物质以及酊剂(含酒精/烈酒)和酏剂(不含酒精/烈酒)。对于文本中提到的每种用途,我们记录了(i)假定的分类群的植物学身份;(ii)植物成分以外的植物来源或其他来源的植物科;(iii)报告的植物部位;(iv)配方编号;(v)配方名称;(vi)成分的俗名;(vii)描述的症状、疾病或特定用途;(viii)我们对描述症状或疾病的现代(即生物医学)解释;(ix)给药方式;以及(x)我们将特定用途归入的使用类别。我们还将克鲁姆洛夫草药师的药用植物与旧手稿和区域调查中描述的物种进行了交叉核对,并将其用途与当代植物用途进行了比较。
本文介绍了一个生成的数据库,其中包含基于 70 个植物类群和其他成分的 46 种药物的 348 种使用报告。此外,我们还研究了一些模式,例如推荐豆科草药治疗呼吸系统问题和菊科草药治疗呼吸系统和心血管问题。胃肠道使用报告基于天门冬科、柏科和蔷薇科物种。
随着时间的推移失去重要性的疗法以及用于治疗现在可通过常规医学控制的疾病的药物可能是草药学和药物发现研究的有趣起点。尝试重现克鲁姆洛夫草药师保留的配方中的治疗混合物似乎很重要,这提供了更多了解以前药物的实际效果及其治疗活性的机会。获得的数据还可用于寻找新药。