伊维菌素在爱尔兰四个奶牛场治疗失败。
Ivermectin treatment failure on four Irish dairy farms.
作者信息
O'Shaughnessy James, Drought Yvonne, Lynch John, Denny Marian, Hurley Christine, Byrne William, Casey Mícheál, de Waal Theo, Sheehan Maresa
机构信息
1Central Veterinary Research Laboratory, Department of Agriculture, Food and the Marine Laboratories, Backweston, Celbridge, Co. Kildare Ireland.
2School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
出版信息
Ir Vet J. 2019 May 15;72:4. doi: 10.1186/s13620-019-0142-8. eCollection 2019.
We report on the use of the faecal egg count reduction test to evaluate the performance of ivermectin in treating gastrointestinal nematode infections in first grazing season (FGS) calves on four dairy farms in Co. Kilkenny, Ireland. On each farm, FGS calves were injected subcutaneously with ivermectin in accordance with their live weight (day 0). Calves were individually faecal sampled on both day 0 and day 14. Faecal egg counts were determined using the Mini-FLOTAC technique. Composite faecal cultures for each farm were performed on each sampling occasion. The faecal egg count reductions (mode) ranged from 17.3-80.2% with the lower 95% confidence limit ranging from 3.1-72.3% on the four farms, respectively. Ivermectin-resistant nematodes were detected on all farms, with evidence of resistance on one farm. This study highlights the urgent need for Irish producers to reappraise their parasite control practices.
我们报告了使用粪便虫卵计数减少试验来评估伊维菌素在爱尔兰基尔肯尼郡四个奶牛场的首个放牧季节（FGS）犊牛中治疗胃肠道线虫感染的效果。在每个农场，FGS犊牛根据其体重在第0天皮下注射伊维菌素。在第0天和第14天分别对犊牛进行个体粪便采样。使用Mini-FLOTAC技术测定粪便虫卵计数。在每次采样时对每个农场进行混合粪便培养。四个农场的粪便虫卵计数减少率（众数）分别为17.3% - 80.2%，95%置信下限分别为3.1% - 72.3%。在所有农场均检测到对伊维菌素有抗性的线虫，其中一个农场有抗性证据。这项研究凸显了爱尔兰养殖者迫切需要重新评估他们的寄生虫控制措施。
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