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本文引用的文献

1
Investigating anthelmintic efficacy against gastrointestinal nematodes in cattle by considering appropriate probability distributions for faecal egg count data.通过考虑粪便虫卵计数数据的适当概率分布来研究牛胃肠道线虫的驱虫效果。
Int J Parasitol Drugs Drug Resist. 2017 Apr;7(1):71-82. doi: 10.1016/j.ijpddr.2017.01.002. Epub 2017 Jan 16.
2
Confirmation of ivermectin resistance in Ostertagia ostertagi in cattle in New Zealand.新西兰牛体内奥斯特他加虫对伊维菌素耐药性的确认。
Vet Parasitol. 2016 Oct 15;229:139-143. doi: 10.1016/j.vetpar.2016.10.011.
3
Controlling nematodes in dairy calves using targeted selective treatments.采用靶向选择性处理方法控制奶牛犊牛体内的线虫
Vet Parasitol. 2015 Apr 30;209(3-4):221-8. doi: 10.1016/j.vetpar.2015.02.024. Epub 2015 Mar 1.
4
Widespread anthelmintic resistance in European farmed ruminants: a systematic review.欧洲养殖反刍动物中广泛存在的驱虫抗性:一项系统综述。
Vet Rec. 2015 May 23;176(21):546. doi: 10.1136/vr.102982. Epub 2015 Mar 11.
5
Detection of anthelmintic resistance on two Irish beef research farms.在爱尔兰的两个肉牛研究农场检测抗蠕虫药耐药性。
Vet Rec. 2014 Aug 2;175(5):120. doi: 10.1136/vr.102556. Epub 2014 Jun 5.
6
Anthelmintic resistance in cattle nematodes in the US.美国牛线虫的驱虫剂耐药性。
Vet Parasitol. 2014 Jul 30;204(1-2):3-11. doi: 10.1016/j.vetpar.2014.03.017. Epub 2014 Mar 25.
7
Mini-FLOTAC, an innovative direct diagnostic technique for intestinal parasitic infections: experience from the field.迷你 FLOTAC,一种创新的肠道寄生虫感染直接诊断技术:来自现场的经验。
PLoS Negl Trop Dis. 2013 Aug 1;7(8):e2344. doi: 10.1371/journal.pntd.0002344. Print 2013.
8
Morphological identification of parasitic nematode infective larvae of small ruminants and cattle: a practical lab guide.小型反刍动物和牛寄生线虫感染性幼虫的形态学鉴定:实用实验室指南
Onderstepoort J Vet Res. 2013 Mar 13;80(1):539. doi: 10.4102/ojvr.v80i1.539.
9
Novel insights in the faecal egg count reduction test for monitoring drug efficacy against gastrointestinal nematodes of veterinary importance.用于监测抗兽医重要性胃肠道线虫药物疗效的粪便虫卵计数减少试验的新见解。
Vet Parasitol. 2012 Sep 10;188(3-4):391-6. doi: 10.1016/j.vetpar.2012.03.020. Epub 2012 Mar 20.
10
An inconvenient truth: global worming and anthelmintic resistance.一个尴尬的事实:全球变暖与驱虫药抗药性。
Vet Parasitol. 2012 May 4;186(1-2):70-8. doi: 10.1016/j.vetpar.2011.11.048. Epub 2011 Nov 20.

伊维菌素在爱尔兰四个奶牛场治疗失败。

Ivermectin treatment failure on four Irish dairy farms.

作者信息

O'Shaughnessy James, Drought Yvonne, Lynch John, Denny Marian, Hurley Christine, Byrne William, Casey Mícheál, de Waal Theo, Sheehan Maresa

机构信息

1Central Veterinary Research Laboratory, Department of Agriculture, Food and the Marine Laboratories, Backweston, Celbridge, Co. Kildare Ireland.

2School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland.

出版信息

Ir Vet J. 2019 May 15;72:4. doi: 10.1186/s13620-019-0142-8. eCollection 2019.

DOI:10.1186/s13620-019-0142-8
PMID:31123583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6521450/
Abstract

We report on the use of the faecal egg count reduction test to evaluate the performance of ivermectin in treating gastrointestinal nematode infections in first grazing season (FGS) calves on four dairy farms in Co. Kilkenny, Ireland. On each farm, FGS calves were injected subcutaneously with ivermectin in accordance with their live weight (day 0). Calves were individually faecal sampled on both day 0 and day 14. Faecal egg counts were determined using the Mini-FLOTAC technique. Composite faecal cultures for each farm were performed on each sampling occasion. The faecal egg count reductions (mode) ranged from 17.3-80.2% with the lower 95% confidence limit ranging from 3.1-72.3% on the four farms, respectively. Ivermectin-resistant nematodes were detected on all farms, with evidence of resistance on one farm. This study highlights the urgent need for Irish producers to reappraise their parasite control practices.

摘要

我们报告了使用粪便虫卵计数减少试验来评估伊维菌素在爱尔兰基尔肯尼郡四个奶牛场的首个放牧季节(FGS)犊牛中治疗胃肠道线虫感染的效果。在每个农场,FGS犊牛根据其体重在第0天皮下注射伊维菌素。在第0天和第14天分别对犊牛进行个体粪便采样。使用Mini-FLOTAC技术测定粪便虫卵计数。在每次采样时对每个农场进行混合粪便培养。四个农场的粪便虫卵计数减少率(众数)分别为17.3% - 80.2%,95%置信下限分别为3.1% - 72.3%。在所有农场均检测到对伊维菌素有抗性的线虫,其中一个农场有抗性证据。这项研究凸显了爱尔兰养殖者迫切需要重新评估他们的寄生虫控制措施。