Vitreoretina Services, MGM Eye Institute, Raipur, India.
Raj Retina and Eye Care Hospital, Patna, Bihar, India.
Indian J Ophthalmol. 2019 Jun;67(6):962-964. doi: 10.4103/ijo.IJO_768_18.
Oculocutaneous albinism is characterized by partial or complete absence of melanin in retinal pigment epithelium (RPE) and uveal melanocytes. Absence of typical fundal background from RPE and choroid makes it difficult to diagnose retinal disorders in ocular albinism. Lack of melanin in RPE makes the laser photocoagulation very challenging in these cases. This report presents a unique case of preterm infant of oculocutaneous albinism diagnosed as aggressive posterior retinopathy of prematurity (APROP), which was successfully treated with diode laser photocoagulation. The parameters of the laser used in this case were higher than usual, just enough to achieve blanching of retina. This report highlights the fact that the diagnosis of APROP and its treatment with laser is challenging in the presence of oculocutaneous albinism, but it is possible to achieve complete regression using diode laser at higher parameters.
眼皮肤白化病的特征是视网膜色素上皮 (RPE) 和葡萄膜黑素细胞中部分或完全缺乏黑色素。由于 RPE 和脉络膜缺乏典型的眼底背景，因此很难在眼部白化病中诊断视网膜疾病。RPE 中缺乏黑色素使得在这些情况下激光光凝治疗极具挑战性。本报告介绍了一例独特的眼皮肤白化病早产儿病例，该患儿被诊断为侵袭性早产儿后部视网膜病变 (APROP)，经二极管激光光凝治疗后成功治愈。本病例中使用的激光参数高于常规参数，仅足以使视网膜变白。本报告强调了这样一个事实，即在存在眼皮肤白化病的情况下，APROP 的诊断及其激光治疗极具挑战性，但使用更高参数的二极管激光可以实现完全消退。
