Division of Gastroenterology, Hepatology & Nutrition, Boston Children's Hospital, Boston, MA.
Division of Gastroenterology, Hepatology & Nutrition, Boston Children's Hospital, Boston, MA.
J Pediatr. 2019 Aug;211:139-145.e1. doi: 10.1016/j.jpeds.2019.04.023. Epub 2019 May 23.
To determine whether clinical and patient-reported outcomes differ in children receiving blenderized diets compared with conventional formula.
We conducted a prospective cohort study of 70 children aged 1-18 years receiving blenderized diets vs conventional formula via feeding tube. We assessed rates of hospitalization and visits to the emergency department (ED) at Boston Children's Hospital in 2017 and Likert scale addressing satisfaction with feeding regimen; Pediatric Gastroesophageal Reflux Disease Symptom and Quality of Life Questionnaire; Pediatric Quality of Life Inventory; and Pediatric Quality of Life Inventory Gastrointestinal Symptoms Scale.
Participants receiving blenderized diets (n = 42, 60%) did not differ in demographics or comorbid diagnoses from those receiving conventional formula (n = 28, 40%). Rates of total visits to the ED (0.8 ± 1.5 vs 1.4 ± 2.7, P = .05), total admissions (0.8 ± 1.2 vs 1.7 ± 2.3, P = .01), and respiratory-related admissions (0.2 ± 0.5 vs 0.6 ± 0.8, P = .04) per year were significantly lower in participants receiving blenderized diets, and respiratory-related visits to the ED trended toward significance (0.1 ± 0.4 vs 0.4 ± 0.8, P = .08). Compared with those receiving conventional formula, participants on blenderized diets reported greater satisfaction ratings (Likert scale 4.3 ± 1.0 vs 3.3 ± 1.2, P = .001), lower symptom (0.7 ± 0.8 vs 1.2 ± 1.1, P = .03), and total (0.8 ± 0.8 vs 1.2 ± 1.0, P = .02) scores on Pediatric Gastroesophageal Reflux Disease Symptom and Quality of Life Questionnaire and greater scores on the Pediatric Quality of Life Inventory Gastrointestinal Symptoms Scale, indicating less nausea and vomiting (64.0 ± 22.6 vs 49.0 ± 37.9, P = .02), abdominal pain (65.0 ± 26.8 vs 56.4 ± 33.9, P = .04), diarrhea (87.9 ± 15.5 vs 73.6 ± 26.3, P = .004), and fewer total symptoms (70.2 ± 16.3 vs 62.3 ± 19.6, P = .03).
Blenderized diets are associated with decreased healthcare use, improved symptom scores, and increased patient satisfaction compared with conventional formulas.
确定接受搅拌饮食的儿童与接受常规配方的儿童相比,其临床和患者报告的结果是否存在差异。
我们对 2017 年在波士顿儿童医院接受通过喂养管进行搅拌饮食和常规配方的 70 名 1-18 岁儿童进行了前瞻性队列研究。我们评估了在波士顿儿童医院住院和急诊就诊的比率(2017 年),以及对喂养方案的满意度进行了李克特量表评估;小儿胃食管反流病症状和生活质量问卷;儿科生活质量量表;和儿科生活质量量表胃肠道症状量表。
接受搅拌饮食的患者(n=42,60%)在人口统计学和合并症诊断方面与接受常规配方的患者(n=28,40%)没有差异。每年去急诊的总次数(0.8±1.5 与 1.4±2.7,P=0.05)、总入院次数(0.8±1.2 与 1.7±2.3,P=0.01)和呼吸相关入院次数(0.2±0.5 与 0.6±0.8,P=0.04)在接受搅拌饮食的患者中明显较低,呼吸相关的急诊就诊次数也有显著趋势(0.1±0.4 与 0.4±0.8,P=0.08)。与接受常规配方的患者相比,接受搅拌饮食的患者报告的满意度评分更高(Likert 量表 4.3±1.0 与 3.3±1.2,P=0.001),症状评分(0.7±0.8 与 1.2±1.1,P=0.03)和总评分(0.8±0.8 与 1.2±1.0,P=0.02)较低,小儿胃食管反流病症状和生活质量问卷,以及儿科生活质量量表胃肠道症状量表的评分更高,表明恶心和呕吐的发生率较低(64.0±22.6 与 49.0±37.9,P=0.02)、腹痛(65.0±26.8 与 56.4±33.9,P=0.04)、腹泻(87.9±15.5 与 73.6±26.3,P=0.004)和总症状更少(70.2±16.3 与 62.3±19.6,P=0.03)。
与常规配方相比,搅拌饮食与减少医疗保健使用、改善症状评分和提高患者满意度相关。