Clinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China; School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
Sleep Med. 2019 Jun;58:88-92. doi: 10.1016/j.sleep.2019.01.006. Epub 2019 Jan 15.
To determine the associations between sleep duration and hypertension in Chinese adults.
This longitudinal study analyzed 9851 adults who had participated in at least two rounds of the CHNS (China Health and Nutrition Survey) during 2004-2011. Sleep duration was classified into ≤7, 8, and ≥9 h. Age, sex, residence location, education level, smoking, drinking alcohol, drinking tea, drinking coffee, activity level, and body mass index were adjusted as confounders in a generalized linear mixed model.
The unadjusted analysis showed that compared with a normal sleep duration (8 h), the odds ratios (ORs) for those with short (≤7 h) and long (≥9 h) sleep durations were 1.24 and 1.17, respectively (95% confidence intervals [CIs] = 1.14-1.36 and 1.06-1.29). After adjusting for confounding factors, the effect of a short sleep duration on hypertension was still statistically significant, with an OR of 1.13 (95% CI = 1.04-1.24), while a long sleep duration no longer had a statistically significant effect.
A short sleep duration is an independent risk factor for adult hypertension, whereas a long sleep duration is not in Chinese adults. The prevalence of hypertension should be prevented and controlled by improving the sleep status of adults.
确定中国成年人的睡眠时间与高血压之间的关联。
本纵向研究分析了至少参加过两轮中国健康与营养调查(CHNS)(2004-2011 年)的 9851 名成年人。睡眠时间分为≤7、8 和≥9 小时。在广义线性混合模型中,将年龄、性别、居住地点、教育水平、吸烟、饮酒、饮茶、喝咖啡、活动水平和体重指数作为混杂因素进行调整。
未经调整的分析显示,与正常睡眠时间(8 小时)相比,短(≤7 小时)和长(≥9 小时)睡眠时间的比值比(OR)分别为 1.24 和 1.17(95%置信区间 [CI] 为 1.14-1.36 和 1.06-1.29)。在调整混杂因素后,短睡眠时间对高血压的影响仍具有统计学意义,OR 为 1.13(95% CI 为 1.04-1.24),而长睡眠时间则不再具有统计学意义。
短睡眠时间是成年人高血压的独立危险因素,而长睡眠时间则不是。通过改善成年人的睡眠状况,应预防和控制高血压的患病率。