Lee Dong Hyun, Han Jae Yong, Park Jae Jun, Cheon Jae Hee, Kim Min
Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Korean J Gastroenterol. 2019 May 25;73(5):269-275. doi: 10.4166/kjg.2019.73.5.269.
In patients with inflammatory bowel disease (IBD), ocular extraintestinal manifestations (EIM) are less common than EIM of other systems, but they are clinically important because they can lead to complications that can cause catastrophic damage to the visual acuity and ocular structure. Anterior uveitis and episcleritis are the most common ocular EIM. Involvement of the orbit, posterior segment, and optic nerve can also occur. A variety of treatments are available ranging from topical steroids to systemic immunosuppressive therapies. The treatment of IBD is also essential if the activity of inflammatory bowel disease affects the ocular symptoms.
在炎症性肠病(IBD)患者中,眼部肠外表现(EIM)不如其他系统的EIM常见,但它们在临床上很重要,因为它们可导致并发症,进而对视力和眼部结构造成灾难性损害。前葡萄膜炎和巩膜炎是最常见的眼部EIM。眼眶、眼后段和视神经也可能受累。从局部类固醇到全身免疫抑制疗法,有多种治疗方法可供选择。如果炎症性肠病的活动影响眼部症状,治疗IBD也至关重要。