Kim Yun Sung, Lee Jun
Divisions of Rheumatology, Department of Internal Medicine, Chosun University College of Medicine, Gwangju, Korea.
Divisions of Gastroenterology, Department of Internal Medicine, Chosun University College of Medicine, Gwangju, Korea.
Korean J Gastroenterol. 2019 May 25;73(5):276-284. doi: 10.4166/kjg.2019.73.5.276.
Almost 50% of patients with inflammatory bowel disease (IBD) exhibit at least one extra-intestinal manifestation in their lifetime. Extra-intestinal manifestations of IBD are often associated with the intestinal disease activity, reducing the quality of life of the patient but rarely leading to fatal complications. Musculoskeletal involvement is the most frequent extra-intestinal manifestation of patients with IBD but this rarely occurs before IBD is diagnosed. They are manifested in various forms, such as arthropathy, fibromyalgia, and osteoporosis. Therefore, a multidisciplinary team approach including gastroenterologists and rheumatologists are necessary for optimal treatment. This review focuses on the diagnosis and treatment of musculoskeletal manifestations of IBD from the perspectives of rheumatologists who can assist gastroenterologists.
近50%的炎症性肠病（IBD）患者在其一生中至少会出现一种肠外表现。IBD的肠外表现通常与肠道疾病活动相关，会降低患者的生活质量，但很少导致致命并发症。肌肉骨骼受累是IBD患者最常见的肠外表现，但这种情况很少在IBD确诊之前出现。它们以多种形式表现出来，如关节病、纤维肌痛和骨质疏松症。因此，包括胃肠病学家和风湿病学家在内的多学科团队方法对于优化治疗是必要的。本综述从能够协助胃肠病学家的风湿病学家的角度，重点关注IBD肌肉骨骼表现的诊断和治疗。
