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病例报告:亚急性硬化性全脑炎表现为急性脑炎

Case Report: Subacute Sclerosing Panencephalitis Presenting as Acute Encephalitis.

机构信息

Department of Neurology, King George's Medical University, Lucknow, India.

Department of Microbiology, King George's Medical University, Lucknow, India.

出版信息

Am J Trop Med Hyg. 2019 Jul;101(1):260-262. doi: 10.4269/ajtmh.19-0215.

Abstract

Subacute sclerosing panencephalitis (SSPE) is still a common disease in India which is characterized by a progressive mental decline, myoclonus, periodic encephalographic abnormalities, and raised anti-measles antibody titter in the cerebrospinal fluid. Acute fulminant SSPE is characterized by a rapid course of disease culminating in death, within 6 months. We report of a 10-year-old boy, who came with a 14-day history of continuous involuntary jerky movements of the left half of the body, including the head. There was a highly increased anti-measles IgG antibody titer, both in the cerebrospinal fluid and serum. We conclude that acute rapidly progressive SSPE can present as acute encephalitis syndrome.

摘要

亚急性硬化性全脑炎(SSPE)在印度仍然是一种常见疾病,其特征是进行性精神衰退、肌阵挛、周期性脑电图异常和脑脊液中麻疹抗体滴度升高。急性暴发性 SSPE 的特点是疾病迅速发展,在 6 个月内导致死亡。我们报告了一名 10 岁男孩,他因左半身(包括头部)持续不自主抽搐运动而出现 14 天的病史。脑脊液和血清中的麻疹 IgG 抗体滴度均显著升高。我们得出结论,急性快速进展性 SSPE 可表现为急性脑炎综合征。

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