From the Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Institute of Infection and Global Health, University of Liverpool, Royal Liverpool University and Broadgreen NHS Trust, NIHR Health Protection Research Unit in Emerging and Zoonotic Infections and The Walton Centre Neurology NHS Foundation Trust, Liverpool, L9 7LJ UK
From the Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Institute of Infection and Global Health, University of Liverpool, Royal Liverpool University and Broadgreen NHS Trust, NIHR Health Protection Research Unit in Emerging and Zoonotic Infections and The Walton Centre Neurology NHS Foundation Trust, Liverpool, L9 7LJ UK From the Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Institute of Infection and Global Health, University of Liverpool, Royal Liverpool University and Broadgreen NHS Trust, NIHR Health Protection Research Unit in Emerging and Zoonotic Infections and The Walton Centre Neurology NHS Foundation Trust, Liverpool, L9 7LJ UK.
QJM. 2015 Mar;108(3):177-82. doi: 10.1093/qjmed/hcu113. Epub 2014 May 26.
Encephalitis is the most frequent neurological complication of measles virus infection. This review examines the pathophysiology of measles infection and the presentations, diagnosis and treatment of the four types of measles-induced encephalitis including primary measles encephalitis, acute post-measles encephalitis, measles inclusion body encephalitis and subacute sclerosing panencephalitis. The early symptoms of encephalitis may be non-specific and can be mistakenly attributed to a systemic infection leading to a delay in diagnosis. This review provides a summary of the symptoms that should cause health care workers to suspect measles-induced encephalitis.
脑炎是麻疹病毒感染最常见的神经并发症。本文综述了麻疹感染的病理生理学以及四种类型的麻疹相关性脑炎,包括原发性麻疹脑炎、急性出疹后脑炎、麻疹包涵体脑炎和亚急性硬化性全脑炎的发病机制、临床表现、诊断和治疗。脑炎的早期症状可能是非特异性的,可能被误认为是全身性感染,从而导致诊断延误。本文综述了应引起医务人员警惕麻疹相关性脑炎的症状。