Chiodera P, Volpi R, Cigarini C, Caiazza A, Marchesi C, Rossi G, Camellini L, Guerra M, Coiro V
Gynecol Obstet Invest. 1987;24(1):56-61. doi: 10.1159/000298775.
In order to test possible effects of lysine-vasopressin (LVP) on basal and LH-RH-stimulated LH and FSH release, an intravenous bolus of LVP (0.06 IU/kg body weight) was injected alone or 10 min before LH-RH (100 micrograms i.v.) in 33 normal women in the follicular, periovulatory and luteal phase of their menstrual cycle. The administration of LVP modified neither the basal secretion of the gonadotropins nor the LH-RH-induced LH and FSH release. These data suggest that in humans, vasopressin is not involved in the control of gonadotropin release at the level of the anterior pituitary.
为了测试赖氨酸加压素(LVP)对基础状态以及促性腺激素释放激素(LH - RH)刺激的促黄体生成素(LH)和促卵泡生成素(FSH)释放的可能影响,对33名处于月经周期卵泡期、围排卵期和黄体期的正常女性,单独静脉推注LVP(0.06国际单位/千克体重),或者在静脉注射LH - RH(100微克)前10分钟注射LVP。LVP的给药既未改变促性腺激素的基础分泌,也未改变LH - RH诱导的LH和FSH释放。这些数据表明,在人类中,加压素不参与腺垂体水平对促性腺激素释放的调控。