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赖氨酸加压素在正常女性月经周期中不影响基础状态及促黄体激素释放激素刺激的促黄体生成素和促卵泡激素释放。

Lysine-vasopressin does not affect basal and LH-RH-stimulated LH and FSH release during the menstrual cycle of normal women.

作者信息

Chiodera P, Volpi R, Cigarini C, Caiazza A, Marchesi C, Rossi G, Camellini L, Guerra M, Coiro V

出版信息

Gynecol Obstet Invest. 1987;24(1):56-61. doi: 10.1159/000298775.

DOI:10.1159/000298775
PMID:3114063
Abstract

In order to test possible effects of lysine-vasopressin (LVP) on basal and LH-RH-stimulated LH and FSH release, an intravenous bolus of LVP (0.06 IU/kg body weight) was injected alone or 10 min before LH-RH (100 micrograms i.v.) in 33 normal women in the follicular, periovulatory and luteal phase of their menstrual cycle. The administration of LVP modified neither the basal secretion of the gonadotropins nor the LH-RH-induced LH and FSH release. These data suggest that in humans, vasopressin is not involved in the control of gonadotropin release at the level of the anterior pituitary.

摘要

为了测试赖氨酸加压素(LVP)对基础状态以及促性腺激素释放激素(LH - RH)刺激的促黄体生成素(LH)和促卵泡生成素(FSH)释放的可能影响,对33名处于月经周期卵泡期、围排卵期和黄体期的正常女性,单独静脉推注LVP(0.06国际单位/千克体重),或者在静脉注射LH - RH(100微克)前10分钟注射LVP。LVP的给药既未改变促性腺激素的基础分泌,也未改变LH - RH诱导的LH和FSH释放。这些数据表明,在人类中,加压素不参与腺垂体水平对促性腺激素释放的调控。

相似文献

1
Lysine-vasopressin does not affect basal and LH-RH-stimulated LH and FSH release during the menstrual cycle of normal women.赖氨酸加压素在正常女性月经周期中不影响基础状态及促黄体激素释放激素刺激的促黄体生成素和促卵泡激素释放。
Gynecol Obstet Invest. 1987;24(1):56-61. doi: 10.1159/000298775.
2
Hypersensitivity of the human gonadotrophs to the repeated administration of small doses of LH-RH.人类促性腺细胞对小剂量促黄体生成素释放激素(LH-RH)反复给药的超敏反应。
Horm Res. 1978;9(1):12-21. doi: 10.1159/000178892.
3
Evaluation of oxytocin administration on luteinizing hormone and follicle-stimulating hormone response to luteinizing hormone-releasing hormone during the menstrual cycle of normal women.正常女性月经周期中,催产素给药对促黄体生成素及促卵泡生成素对促黄体生成素释放激素反应的影响评估。
Fertil Steril. 1984 Sep;42(3):396-9. doi: 10.1016/s0015-0282(16)48079-9.
4
Secretion rates of LH and FSH during infusion of LH-FSH/RH in normal women and in patients with secondary amenorrhea: suggestive evidence for two pools of LH and FSH.正常女性和继发性闭经患者输注促黄体生成素-促卵泡生成素释放激素(LH-FSH/RH)期间促黄体生成素(LH)和促卵泡生成素(FSH)的分泌率:提示存在两个LH和FSH池的证据
J Clin Endocrinol Metab. 1976 Jul;43(1):159-67. doi: 10.1210/jcem-43-1-159.
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Inhibition by somatostatin of LH-RH-induced LH release in normal menstruating women.
Gynecol Obstet Invest. 1986;22(1):17-21. doi: 10.1159/000298884.
6
Short-term regulation of LH and FSH secretion in cyclic women. I. Altered pituitary response to a second of two LH-RH injections at short intervals.月经周期正常女性促黄体生成素(LH)和促卵泡生成素(FSH)分泌的短期调节。I. 短期内间隔注射两次促性腺激素释放激素(LH-RH)时垂体的反应变化。
Acta Endocrinol (Copenh). 1978 Feb;87(2):248-58.
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[Study on the functions of synthesis and release of gonadotropins of the pituitary gland in human subjects by LH-RH 2-step test].[采用LH-RH两步试验对人体垂体促性腺激素合成与释放功能的研究]
Nihon Sanka Fujinka Gakkai Zasshi. 1982 Oct;34(10):1684-90.
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LH and FSH responses to luteinizing releasing hormone in normal fertile women.正常育龄女性促黄体生成素(LH)和促卵泡生成素(FSH)对促黄体生成素释放激素的反应。
Metabolism. 1976 Nov;25(11):1275-85. doi: 10.1016/s0026-0495(76)80011-x.
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Pituitary and ovarian response to acute stimulation with LH-RH in normal and anovulatory women.正常和无排卵女性垂体及卵巢对促黄体生成素释放激素急性刺激的反应。
Int J Fertil. 1977;22(1):6-15.
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The effects of estrogen and progesterone on the functional capacity of the gonadotrophs.雌激素和孕激素对促性腺激素细胞功能能力的影响。
J Clin Endocrinol Metab. 1975 Nov;41(5):820-6. doi: 10.1210/jcem-41-5-820.

引用本文的文献

1
Effect of lysine vasopressin on basal and TRH stimulated TSH and PRL release in normal men.
J Endocrinol Invest. 1988 Jul-Aug;11(7):497-500. doi: 10.1007/BF03350168.