关节炎患者的γ-谷氨酰转肽酶水平：与疾病活动的临床及实验室指标的相关性
Gamma glutamyl transpeptidase levels in arthritis: a correlation with clinical and laboratory indices of disease activity.
作者信息
Lowe J R, Pickup M E, Dixon J S, Leatham P A, Rhind V M, Wright V, Downie W W
出版信息
Ann Rheum Dis. 1978 Oct;37(5):428-31. doi: 10.1136/ard.37.5.428.
Abstract
Gamma glutamyl transpeptidase (GGTP) was measured in 62 patients with rheumatoid arthritis (RA) and 27 with osteoarthrosis (OA). The values for GGTP were significantly higher in the subjects with RA compared with the OA group. The prevalence of elevation of GGTP was higher in the RA subjects (77%) than in the OA patients (33%). Levels of GGTP correlated significantly with a number of objective indices of activity of RA in a separate group of 28 patients. Following treatment with penicillamine, GGTP levels showed a significant drop towards normal levels.
摘要
对62例类风湿性关节炎（RA）患者和27例骨关节炎（OA）患者进行了γ-谷氨酰转肽酶（GGTP）检测。与OA组相比，RA患者的GGTP值显著更高。RA患者中GGTP升高的患病率（77%）高于OA患者（33%）。在另一组28例患者中，GGTP水平与RA活动的多项客观指标显著相关。用青霉胺治疗后，GGTP水平显著下降至正常水平。
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