Imai H, Ikuta K, Ueda S, Suehiro S, Yamamoto N, Kato S
Jpn J Cancer Res. 1987 Jul;78(7):648-50.
The effect of neurotropin on human immuno-deficiency virus (HIV) production in a virus-producing MOLT-4 (MOLT-4/HTLV-III) cell line was studied. Culture of the cells for 4 days in the presence of 100 micrograms/ml of neurotropin resulted in a 72% decrease in the number of infectious virus particles released into the culture fluid. A pulse-labeling experiment to analyze the synthesis of HIV proteins suggested that neurotropin may affect the budding process of the virus.
研究了神经妥乐平对产病毒的MOLT-4（MOLT-4/HTLV-III）细胞系中人类免疫缺陷病毒（HIV）产生的影响。在存在100微克/毫升神经妥乐平的情况下将细胞培养4天，导致释放到培养液中的感染性病毒颗粒数量减少了72%。一项分析HIV蛋白合成的脉冲标记实验表明，神经妥乐平可能影响病毒的出芽过程。
