Chen Chia-Chun, Lee Chin-Tse, Chang Shih-Lun, Tsai Meng-Chen
Department of Otorhinolaryngology, Chi Mei Medical Center.
Department of Optometry, Chung Hwa University of Medical Technology.
Medicine (Baltimore). 2019 May;98(22):e15763. doi: 10.1097/MD.0000000000015763.
Palatine tonsil is an extremely rare site for metastatic disease, accounting for 0.8% of malignant tonsillar neoplasms. To the best of our knowledge, this is the first report of metastatic adenocarcinoma in the tonsil treated with wide excision and targeted therapy, with no local recurrence 6 months postoperatively.
A 75-year-old man presented hemoptysis and mild productive cough for 2 weeks.
Palatine tonsil metastasis from lung adenocarcinoma, pT2bN0M1b, stage IVA, was confirmed.
Wide excision of primary lung tumor and metastatic tonsil carcinoma has been performed, and the patient was undergoing targeted therapy with the epidermal growth factor receptor inhibitor afatinib.
There was no local recurrence in the oropharynx 6 months postoperatively.
We aim at highlighting the importance of a thorough evaluation for suspicion of tonsillar enlargement, which might be a sign of a primary malignancy elsewhere.
腭扁桃体是转移性疾病极为罕见的部位，占恶性扁桃体肿瘤的0.8%。据我们所知，这是首例关于经广泛切除和靶向治疗的扁桃体转移性腺癌的报告，术后6个月无局部复发。
一名75岁男性出现咯血和轻度咳痰2周。
确诊为肺腺癌腭扁桃体转移，pT2bN0M1b，IV A期。
已对原发性肺肿瘤和转移性扁桃体癌进行广泛切除，患者正在接受表皮生长因子受体抑制剂阿法替尼的靶向治疗。
术后6个月口咽无局部复发。
我们旨在强调对疑似扁桃体肿大进行全面评估的重要性，扁桃体肿大可能是其他部位原发性恶性肿瘤的迹象。
