Mastronikolis N S, Tsiropoulos G E, Chorianopoulos D, Liava A C H, Stathas T, Papadas T A
Department of Otorhinolaryngology, University of Patras Medical School, Patras, Greece.
Eur Rev Med Pharmacol Sci. 2007 Sep-Oct;11(5):279-82.
Tonsillar metastasis from lung cancer is an extremely rare event and is usually related to metastatic spread of the neoplastic disease to other organs with poor prognosis. We present the unusual case of a 71-year-old man who developed a huge metastasis to the left palatine tonsil from a lung adenocarcinoma. The tumor was exophytic with necrotic and hemorrhagic areas, occupying a large portion of the oropharynx and producing airway obstruction, thus necessitating tracheostomy. Radiation therapy was delivered in an attempt to reduce the size of the tumor. Although a mild decrease of the tonsillar mass was noted, the designed therapy had to be discontinued because of a rapid deterioration of the patient's general condition. The patient finally died of disseminated disease. This case highlights the need for a thorough evaluation of a suspicious tonsillar enlargement, as this may be a sign of a primary malignancy elsewhere in the body.
肺癌发生扁桃体转移极为罕见，通常与肿瘤性疾病转移至其他器官有关，预后较差。我们报告了一例不寻常的病例，一名71岁男性因肺腺癌发生巨大转移至左侧腭扁桃体。肿瘤呈外生性，伴有坏死和出血区域，占据口咽的大部分，导致气道阻塞，因此需要进行气管切开术。尝试进行放射治疗以缩小肿瘤大小。尽管扁桃体肿块略有缩小，但由于患者全身状况迅速恶化，不得不停止既定治疗。患者最终死于播散性疾病。该病例强调了对可疑扁桃体肿大进行全面评估的必要性，因为这可能是身体其他部位原发性恶性肿瘤的迹象。
