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Time spent being sedentary: an emerging risk factor for poor health.

作者信息

Salman David, Farooqi Mustafa, McGregor Alison, Majeed Azeem

机构信息

Department of Primary Care & Public Health; MSk Laboratory, Department of Surgery & Cancer, Imperial College London, London, UK.

Department of Primary Care & Public Health, Imperial College London, London.

出版信息

Br J Gen Pract. 2019 Jun;69(683):278-279. doi: 10.3399/bjgp19X703781.

DOI:10.3399/bjgp19X703781
PMID:31147321
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6532816/
Abstract
摘要

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本文引用的文献

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Reducing sitting time versus adding exercise: differential effects on biomarkers of endothelial dysfunction and metabolic risk.减少久坐时间与增加运动：对血管内皮功能障碍和代谢风险生物标志物的不同影响。
Sci Rep. 2018 Jun 5;8(1):8657. doi: 10.1038/s41598-018-26616-w.
2
GPs' knowledge, use, and confidence in national physical activity and health guidelines and tools: a questionnaire-based survey of general practice in England.全科医生对国家体力活动和健康指南及工具的了解、使用和信心：对英格兰普通实践的基于问卷调查的研究。
Br J Gen Pract. 2017 Oct;67(663):e668-e675. doi: 10.3399/bjgp17X692513. Epub 2017 Aug 14.
3
Sedentary Behavior Research Network (SBRN) - Terminology Consensus Project process and outcome.久坐行为研究网络（SBRN）——术语共识项目的过程与成果。
Int J Behav Nutr Phys Act. 2017 Jun 10;14(1):75. doi: 10.1186/s12966-017-0525-8.
4
The microbiome of professional athletes differs from that of more sedentary subjects in composition and particularly at the functional metabolic level.专业运动员的微生物组在组成上与久坐不动的受试者不同，特别是在功能代谢水平上。
Gut. 2018 Apr;67(4):625-633. doi: 10.1136/gutjnl-2016-313627. Epub 2017 Mar 30.
5
Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality? A harmonised meta-analysis of data from more than 1 million men and women.体育活动是否能减弱甚至消除久坐时间与死亡率之间的有害关联？一项针对超过 100 万男性和女性数据的综合荟萃分析。
Lancet. 2016 Sep 24;388(10051):1302-10. doi: 10.1016/S0140-6736(16)30370-1. Epub 2016 Jul 28.
6
Endothelial dysfunction following prolonged sitting is mediated by a reduction in shear stress.长时间坐着后出现的内皮功能障碍是由剪切应力降低介导的。
Am J Physiol Heart Circ Physiol. 2016 Mar 1;310(5):H648-53. doi: 10.1152/ajpheart.00943.2015. Epub 2016 Jan 8.
7
Regular Exercise Enhances the Immune Response Against Microbial Antigens Through Up-Regulation of Toll-like Receptor Signaling Pathways.规律运动通过上调Toll样受体信号通路增强针对微生物抗原的免疫反应。
Cell Physiol Biochem. 2015;37(2):735-46. doi: 10.1159/000430391. Epub 2015 Sep 11.
8
Understanding the Cellular and Molecular Mechanisms of Physical Activity-Induced Health Benefits.理解运动促进健康的细胞和分子机制。
Cell Metab. 2015 Jul 7;22(1):4-11. doi: 10.1016/j.cmet.2015.05.011. Epub 2015 Jun 11.
9
Sedentary time and its association with risk for disease incidence, mortality, and hospitalization in adults: a systematic review and meta-analysis.久坐时间与成年人疾病发病率、死亡率和住院率的关系：系统评价和荟萃分析。
Ann Intern Med. 2015 Jan 20;162(2):123-32. doi: 10.7326/M14-1651.
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Exercise as an anti-inflammatory therapy for rheumatic diseases-myokine regulation.运动作为风湿性疾病的抗炎治疗——肌因子调节。
Nat Rev Rheumatol. 2015 Feb;11(2):86-97. doi: 10.1038/nrrheum.2014.193. Epub 2014 Nov 25.