Dirección General de Investigación Científica y Tecnológica, Centro Multidisciplinario de Investigaciones Tecnológicas, Universidad Nacional de Asunción, San Lorenzo 1039, Paraguay.
Facultad de Ciencias Exactas y Naturales, Departamento de Biotecnología, Universidad Nacional de Asunción, San Lorenzo 1039, Paraguay.
Toxins (Basel). 2019 May 30;11(6):308. doi: 10.3390/toxins11060308.
Alcoholic beverages can be contaminated with mycotoxins. Ochratoxin A (OTA) is the most frequently detected mycotoxinin wine and is produced by several species of This mycotoxin is nephrotoxic and carcinogenic. In beer, the most commonly identified mycotoxin is deoxynivalenol (DON). Ingestion of food contaminated with DON has been associated with adverse gastrointestinal effects. Despite the harmful effects of mycotoxins on health, there are no regulations regarding their limits in alcoholic beverages in Paraguay. Here we determine the presence of OTA and DON in wine and beer, respectively. Four commercial brands of wine and twenty-nine brands of craft and industrial beerwere tested by the Agra quant ELISA method. One brand of wine was positive for OTA and seven brands of beer (one of them craft) were positive for DON. The values found for both toxins are below the recommended maximum intake proposed by international standards. Giving the high consumption of these products in the country, regulations and monitoring systems mustbe established to check the maximum levels of mycotoxins allowed in alcoholic beverages.
酒精饮料可能受到真菌毒素的污染。赭曲霉毒素 A(OTA)是葡萄酒中最常检测到的真菌毒素,由几种曲霉菌产生。这种真菌毒素具有肾毒性和致癌性。在啤酒中,最常见的真菌毒素是脱氧雪腐镰刀菌烯醇(DON)。摄入受 DON 污染的食物与胃肠道不良反应有关。尽管真菌毒素对健康有有害影响,但巴拉圭没有关于其在酒精饮料中限量的规定。在这里,我们分别确定了葡萄酒和啤酒中 OTA 和 DON 的存在。我们用 Agra quant ELISA 法测试了四个商业品牌的葡萄酒和 29 个工艺和工业品牌的啤酒。一个品牌的葡萄酒呈 OTA 阳性,七个品牌的啤酒(其中一个是工艺啤酒)呈 DON 阳性。两种毒素的检测值均低于国际标准建议的最大允许摄入量。鉴于该国对这些产品的高消费,必须建立法规和监测系统,以检查酒精饮料中允许的真菌毒素最大含量。