Gufoni手法治疗水平半规管良性阵发性位置性眩晕（HC-BPPV）的即刻疗效：一项荟萃分析
Immediate efficacy of Gufoni maneuver for horizontal canal benign paroxysmal positional vertigo (HC-BPPV): a meta-analysis.
作者信息
Fu Wei, Han Junliang, Chang Ning, Wei Dong, Bai Ya, Wang Yuanyuan, He Feng, Wang Xiaoming
机构信息
Department of Geriatrics, Xijing Hospital, Fourth Military Medical University, No. 15, Changle West Road, Xi'an, Shaanxi 710032, China.
Department of Neurology, Xijing Hospital, Fourth Military Medical University, No. 15, Changle West Road, Xi'an, Shaanxi 710032, China.
出版信息
Auris Nasus Larynx. 2020 Feb;47(1):48-54. doi: 10.1016/j.anl.2019.05.002. Epub 2019 May 28.
OBJECTIVE
This meta-analysis aims to systematically measure the immediate efficacy of the Gufoni maneuver for horizontal canal benign paroxysmal positional vertigo (HC-BPPV).
METHODS
A extensive search electronic databases, including PubMed, Embase, Web of Science and Cochrane library, were searched until to September 1, 2018 for relevant articles. We selected only randomized clinical trials studying with treatment of HC-BPPV employ by the Gufoni maneuver.
RESULTS
Five randomized clinical trials were included in the current meta-analysis with a total of 714 HC-BPPV patients. The meta-analysis revealed that Gufoni maneuver had a higher immediate recovery rate than sham maneuver in treatment of HC-BPPV (risk ratio = 2.68, 95% CI, 1.54-4.65, p < 0.01). No difference was observed in immediate recovery rate between Gufoni maneuver and other maneuvers (risk ratio = 1.18, 95% CI, 0.99-1.41, p = 0.06). And Gufoni maneuver had a similar otolith switch rate with other maneuvers (risk ratio = 2.13, 95% CI, 0.56-8.07, p = 0.27).
CONCLUSION
Gufoni maneuver has a satisfactory immediate efficacy for HC-BPPV and does not increase otolith switch rate.
目的
本荟萃分析旨在系统评估Gufoni手法治疗水平半规管良性阵发性位置性眩晕（HC-BPPV）的即时疗效。
方法
广泛检索电子数据库，包括PubMed、Embase、科学网和Cochrane图书馆，检索截至2018年9月1日的相关文章。我们仅选择采用Gufoni手法治疗HC-BPPV的随机临床试验。
结果
本荟萃分析纳入了5项随机临床试验，共714例HC-BPPV患者。荟萃分析显示，在治疗HC-BPPV方面，Gufoni手法的即时恢复率高于假手法（风险比=2.68，95%CI，1.54-4.65，p<0.01）。Gufoni手法与其他手法的即时恢复率无差异（风险比=1.18，95%CI，0.99-1.41，p=0.06）。且Gufoni手法与其他手法的耳石复位率相似（风险比=2.13，95%CI，0.56-8.07，p=0.27）。
结论
Gufoni手法治疗HC-BPPV具有令人满意的即时疗效，且不会增加耳石复位率。
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