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良性阵发性位置性眩晕向地性水平半规管随机临床试验。

Randomized clinical trial for geotropic horizontal canal benign paroxysmal positional vertigo.

机构信息

Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seoul, Korea.

出版信息

Neurology. 2012 Aug 14;79(7):700-7. doi: 10.1212/WNL.0b013e3182648b8b. Epub 2012 Aug 1.

DOI:10.1212/WNL.0b013e3182648b8b
PMID:22855868
Abstract

OBJECTIVES

To determine the immediate and long-term therapeutic efficacies of barbecue rotation and Gufoni maneuvers, a randomized, prospective, and sham-controlled study was conducted in patients with the geotropic type of benign paroxysmal positional vertigo involving the horizontal semicircular canal (HC-BPPV).

METHODS

In 10 nationwide dizziness clinics in Korea, 170 consecutive patients (107 women, age range 11-97 years, mean age ± SD 61 ± 15 years, median = 61 years) with geotropic HC-BPPV were randomly assigned to barbecue rotation (n = 56), Gufoni (n = 64), or sham maneuver (n = 50). An immediate response was determined within 1 hour after a maximum of 2 trials of each maneuver on the visit day. We also assessed the cumulative results of each maneuver by following up the patients for 1 month.

RESULTS

After a maximum of 2 maneuvers on the initial visit day, barbecue rotation (38 of 55 [69.1%]) and Gufoni (39 of 64 [60.9%]) maneuvers showed better responses than the sham maneuver (17 of 48 [35.4%]). The cumulative therapeutic effects were also better with barbecue rotation (p = 0.006) and Gufoni (p = 0.031) maneuvers than with the sham maneuver. However, therapeutic efficacies did not differ between the barbecue rotation and Gufoni groups in terms of both immediate (p = 0.46) and long-term (p = 0.10) outcomes.

CONCLUSION

Using a prospective randomized trial, we demonstrated that barbecue rotation and Gufoni maneuvers are effective in treating geotropic HC-BPPV.

CLASSIFICATION OF EVIDENCE

This study provides Class I evidence that barbecue rotation and Gufoni maneuvers are effective in the treatment of geotropic HC-BPPV.

摘要

目的

确定烧烤旋转和 Gufoni 手法在水平半规管良性阵发性位置性眩晕(HC-BPPV)中向地型的即时和长期治疗效果。

方法

在韩国的 10 家全国性头晕诊所中,170 名连续患者(107 名女性,年龄 11-97 岁,平均年龄±标准差 61±15 岁,中位数=61 岁)被随机分配到烧烤旋转组(n=56)、Gufoni 组(n=64)或假手法组(n=50)。在就诊当天,最多进行 2 次每种手法的试验后 1 小时内确定即时反应。我们还通过随访患者 1 个月来评估每种手法的累积结果。

结果

在初始就诊日进行最多 2 次手法后,烧烤旋转(55 例中的 38 例[69.1%])和 Gufoni(64 例中的 39 例[60.9%])手法的反应优于假手法(48 例中的 17 例[35.4%])。烧烤旋转(p=0.006)和 Gufoni(p=0.031)手法的累积治疗效果也优于假手法。然而,在即时(p=0.46)和长期(p=0.10)结果方面,烧烤旋转和 Gufoni 组之间的治疗效果没有差异。

结论

使用前瞻性随机试验,我们证明了烧烤旋转和 Gufoni 手法在治疗向地型 HC-BPPV 方面是有效的。

证据分类

本研究提供了 I 级证据,证明烧烤旋转和 Gufoni 手法在治疗向地型 HC-BPPV 方面是有效的。

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