School of Medicine in Bahia, Post-Graduate Program in Health Sciences, Federal University of Bahia (UFBA), Salvador, Bahia, Brazil.
School of Medicine in Bahia, Post-Graduate Program in Health Sciences, Federal University of Bahia (UFBA), Salvador, Bahia, Brazil.
Ann Hepatol. 2019 Sep-Oct;18(5):751-756. doi: 10.1016/j.aohep.2019.03.009. Epub 2019 May 13.
Viral hepatitis is an endemic and epidemic disease of relevance in public health. This study estimated the frequency of viral hepatitis by occupational and non-occupational infections and analyzed the factors associated with case notifications in Brazil from 2007 to 2014.
This was an exploratory epidemiological study using the Notifiable Diseases Information System database. Descriptive and multivariate analyses were performed.
The frequency of viral hepatitis by occupational infections was 0.7%, of which 1.3% were due to hepatitis A virus (HAV), 45.1% hepatitis B virus (HBV), and 45.3% hepatitis C virus (HCV). There was a significant association of the disease with female sex [AOR=1.31; P=0.048], schooling [AOR=1.71; P<0.001], occupation [AOR=2.74; P<0.001], previous contact with an HBV or HCV-infected patient [AOR=5.77; P<0.001], exposure to accidents with biological materials [AOR=99.82; P<0.001], and hepatitis B vaccination [AOR=0.73; P=0.033].
While there was a low frequency of viral hepatitis by occupational infections in Brazil from 2007 to 2014, these findings might be underreported and have been associated with individual and occupational characteristics. This reinforces the need for the adoption of prevention strategies in the workplace and for completeness of case notifications.
病毒性肝炎是一种具有公共卫生相关性的地方性和流行性疾病。本研究估计了 2007 年至 2014 年期间巴西职业和非职业感染的病毒性肝炎发病率,并分析了与病例报告相关的因素。
本研究采用传染病报告信息系统数据库进行了一项探索性的流行病学研究。进行了描述性和多变量分析。
职业感染引起的病毒性肝炎发病率为 0.7%,其中甲型肝炎病毒(HAV)占 1.3%,乙型肝炎病毒(HBV)占 45.1%,丙型肝炎病毒(HCV)占 45.3%。该疾病与女性[比值比(OR)=1.31;P=0.048]、教育程度[OR=1.71;P<0.001]、职业[OR=2.74;P<0.001]、与 HBV 或 HCV 感染者有过接触[OR=5.77;P<0.001]、接触生物材料所致意外[OR=99.82;P<0.001]和乙型肝炎疫苗接种[OR=0.73;P=0.033]有关。
2007 年至 2014 年期间,巴西职业感染引起的病毒性肝炎发病率较低,但这些发现可能存在漏报,且与个人和职业特征有关。这加强了在工作场所采取预防策略和提高病例报告完整性的必要性。