El-Hawy Raghda M, Ashmawy Mohamed I, Kamal Menna M, Khamis Hager A, Abo El-Hamed Naglaa M, Eladely Gehad I, Abdo Mayar H, Hashem Yosra, Ramadan Marwa, Hamdy Dalia A
Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Faculty of Science, Alexandria University, Alexandria, Egypt.
Eur J Hosp Pharm. 2017 Nov;24(6):349-354. doi: 10.1136/ejhpharm-2016-001032. Epub 2016 Oct 28.
To assess knowledge, attitude and practice (KAP) of antimicrobial self-medication among a convenience sample of population in Alexandria, Egypt.
A descriptive cross-sectional study using a self-administrated semi-constructed questionnaire. A convenience sample of 359 participants was studied using appropriate consent. The questionnaire had four sections: demographics, KAP, professional medical knowledge and attitude of children caregivers toward antimicrobial self-medication. The questionnaire was initially constructed in English and then translated into its final Arabic version. The Arabic version was pilot-tested and face-validated. Descriptive and quantitative analysis were performed using SPSS (V.20.0).
Approximately 64% (231) of the studied population used antibiotics without prescription in the past 12 months. This was significantly correlated with female gender and lack of knowledge. The main reason for self-medication was due to saving time and effort (109, 47%) followed by not preferring doctor visits (89, 39%). More than 60% of cases used amoxicillin-clavulanic acid. The main sources of antibiotics were leftovers from previously prescribed pharmaceuticals and those purchased from community pharmacies. 85 participants were young children caregivers of which 18 (21%) reported administering antibiotics to their children without consulting a physician. Out of 115 who claimed attaining medical background, only 30 (26%) managed to answer section 3 correctly with 23 of them reporting antibiotic self-medication.
This study showed an increased tendency towards antibiotic self-medication among Alexandrian adults and children that was not significantly decreased in population with medical background. The reasons discussed within the study should be further addressed to decrease such practice.
评估埃及亚历山大港便利抽样人群中抗菌药物自我药疗的知识、态度和行为（KAP）。
采用自行设计的半结构式问卷进行描述性横断面研究。通过适当的知情同意，对359名参与者的便利样本进行了研究。问卷有四个部分：人口统计学、KAP、专业医学知识以及儿童看护者对抗菌药物自我药疗的态度。问卷最初用英文构建，然后翻译成最终的阿拉伯语版本。阿拉伯语版本进行了预测试和表面效度验证。使用SPSS（V.20.0）进行描述性和定量分析。
在过去12个月中，约64%（231人）的研究人群在没有处方的情况下使用了抗生素。这与女性性别和知识缺乏显著相关。自我药疗的主要原因是节省时间和精力（109人，47%），其次是不喜欢看医生（89人，39%）。超过60%的病例使用阿莫西林 - 克拉维酸。抗生素的主要来源是先前处方药物的剩余部分以及从社区药店购买的药物。85名参与者是幼儿看护者，其中18人（21%）报告在未咨询医生的情况下给孩子使用了抗生素。在115名声称有医学背景的人中，只有30人（26%）能够正确回答第3部分，其中23人报告有抗生素自我药疗行为。
本研究表明，亚历山大港的成年人和儿童中抗生素自我药疗的趋势有所增加，在有医学背景的人群中这种趋势并没有显著降低。研究中讨论的原因应进一步加以解决，以减少这种行为。
