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瑞典南部地区葡萄膜炎的流行病学。

Epidemiology of uveitis in a region of southern Sweden.

机构信息

The Eye Unit, Höglandssjukhuset Eksjö, Eksjö, Sweden.

St. Erik's Eye Hospital, Stockholm, Sweden.

出版信息

Acta Ophthalmol. 2020 Feb;98(1):32-35. doi: 10.1111/aos.14130. Epub 2019 Jun 4.

DOI:10.1111/aos.14130
PMID:31161663
Abstract

PURPOSE

To analyse the distribution and treatment of uveitis in a region of southern Sweden and compare the results with previously reported European data.

METHODS

Anonymized data for all individuals in the region with an ICD-10 diagnosis that indicated uveitis between 2013 and 2017 were extracted from a computerized healthcare register.

RESULTS

In total, 2483 patients were diagnosed with uveitis during 2013-2017. Anterior uveitis was diagnosed in 93%, intermediate in 1%, posterior in 5% and panuveitis in 1% of cases. An associated diagnosis was found in 14%, and the five most common associated diseases were herpes simplex/zoster (4.9%), inflammatory bowel disease (2.2%), rheumatic arthritis (1.9%), ankylosing spondylitis (1.8%) and sarcoidosis (1.8%). Systemic treatment was used in 14% of the cases. The period prevalence of uveitis was 700 cases per 100 000 individuals, and the yearly incidence was estimated to 108 cases/year/100 000 individuals.

CONCLUSIONS

Compared with studies from referral clinics, this community-based study had a large proportion of anterior uveitis (93%) and uveitis without associated diagnosis (86%). Uveitis was also much more common among elderly than shown in previous research. The distribution of possible associated diagnosis conformed to several previous European studies.

摘要

目的

分析瑞典南部一个地区的葡萄膜炎分布和治疗情况,并将结果与先前报道的欧洲数据进行比较。

方法

从一个计算机化的医疗保健登记处提取了 2013 年至 2017 年间该地区所有 ICD-10 诊断为葡萄膜炎的个体的匿名数据。

结果

在 2013-2017 年期间,共有 2483 名患者被诊断为葡萄膜炎。93%为前葡萄膜炎,1%为中间葡萄膜炎,5%为后葡萄膜炎,1%为全葡萄膜炎。14%的患者伴有其他疾病,最常见的五种伴发疾病为单纯疱疹/带状疱疹(4.9%)、炎症性肠病(2.2%)、风湿性关节炎(1.9%)、强直性脊柱炎(1.8%)和结节病(1.8%)。14%的患者接受了全身治疗。葡萄膜炎的时期患病率为每 10 万人中有 700 例,年发病率估计为每 10 万人每年 108 例。

结论

与来自转诊诊所的研究相比,这项基于社区的研究中,前葡萄膜炎(93%)和无相关诊断的葡萄膜炎(86%)比例较大。老年患者的葡萄膜炎也比以前的研究更为常见。可能的相关诊断分布与几项以前的欧洲研究相符。

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