泰国东北部一家眼科转诊中心的葡萄膜炎模式。
Pattern of uveitis in a referral ophthalmology center in Northeastern Thailand.
作者信息
Wannapanich Trakanta, Chuenchaem Waraporn, Luanratanakorn Patanaree, Laovirojjanakul Wipada
机构信息
Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
出版信息
J Ophthalmic Inflamm Infect. 2024 May 31;14(1):23. doi: 10.1186/s12348-024-00400-6.
PURPOSE
To report the characteristics and epidemiology of uveitis in a university-based referral center in northeastern Thailand and review the uveitis patterns present in various regions worldwide.
METHODS
A retrospective review of all medical records for new patients visiting the uveitis clinic at Srinagarind hospital, Khon Kaen University, between August 2016 and June 2021, was conducted.
RESULTS
A total of 522 uveitis patients were included in this study. Disease etiologies were categorized as non-infectious 35.8% (187/522), infectious 32.8% (171/522), and undetermined cause 31.4% (164/522). Specific diagnoses were established in 68.6% of cases. Vogt-Koyanagi-Harada (VKH) (14.2%) was identified as the most common specific diagnosis, and tuberculosis (6.7%) ranked highest among infectious causes.
CONCLUSIONS
Although non-infectious uveitis is observed predominantly in this region, the proportion of infectious uveitis is relatively more common than in developed countries. We have found no cause for one-third of our patients despite the utilization of PCR and serology for diagnostic purposes.
目的
报告泰国东北部一所大学转诊中心葡萄膜炎的特征和流行病学情况，并回顾全球不同地区的葡萄膜炎模式。
方法
对2016年8月至2021年6月期间孔敬大学诗里拉吉医院葡萄膜炎诊所新患者的所有病历进行回顾性研究。
结果
本研究共纳入522例葡萄膜炎患者。疾病病因分为非感染性35.8%（187/522）、感染性32.8%（171/522）和病因不明31.4%（164/522）。68.6%的病例确诊了具体病因。伏格特-小柳-原田病（VKH）（14.2%）是最常见的具体诊断，结核病（6.7%）在感染性病因中占比最高。
结论
虽然该地区主要观察到非感染性葡萄膜炎，但感染性葡萄膜炎的比例相对发达国家更为常见。尽管使用了聚合酶链反应（PCR）和血清学进行诊断，但我们仍有三分之一的患者病因不明。
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