从一名人类患者中分离出的携带 mcr-3.1 基因的 IncHI2 质粒的多药和黏菌素耐药鼠伤寒沙门氏菌 4,[5],12:i:- 血清型 34。
Multidrug- and colistin-resistant Salmonella enterica 4,[5],12:i:- sequence type 34 carrying the mcr-3.1 gene on the IncHI2 plasmid recovered from a human.
机构信息
Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
Department of Population Health and Pathobiology, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USA.
出版信息
J Med Microbiol. 2019 Jul;68(7):986-990. doi: 10.1099/jmm.0.001012. Epub 2019 Jun 4.
Abstract
A colistin-resistant Salmonella enterica 4, [5],12:i:- sequence type (ST) 34 harbouring mcr-3.1 was recovered from a patient who travelled to China 2 weeks prior to diarrhoea onset. Genomic analysis revealed the presence of the mcr-3.1 gene located in the globally disseminated IncHI2 plasmid, highlighting the intercontinental dissemination of the colistin-resistant S. enterica 4, [5],12:i:- ST34 pandemic clone.
摘要
从一名腹泻前 2 周前往中国旅行的患者中分离到一株携带 mcr-3.1 的耐药性沙门氏菌 4, [5],12:i:- 血清型 34，该菌对黏菌素耐药。基因分析显示 mcr-3.1 基因位于广泛传播的 IncHI2 质粒上，这突显了耐黏菌素的沙门氏菌 4, [5],12:i:- ST34 流行克隆的洲际传播。
相似文献
1
Multidrug- and colistin-resistant Salmonella enterica 4,[5],12:i:- sequence type 34 carrying the mcr-3.1 gene on the IncHI2 plasmid recovered from a human.
J Med Microbiol. 2019 Jul;68(7):986-990. doi: 10.1099/jmm.0.001012. Epub 2019 Jun 4.
2
Characterization of a colistin-resistant Salmonella enterica 4,[5],12:i:- harbouring mcr-3.2 on a variant IncHI-2 plasmid identified in Canada.
J Med Microbiol. 2018 Dec;67(12):1673-1675. doi: 10.1099/jmm.0.000854. Epub 2018 Oct 23.
3
Plasmid-borne colistin resistance gene mcr-1 in a multidrug resistant Salmonella enterica serovar Typhimurium isolate from an infant with acute diarrhea in China.
Int J Infect Dis. 2021 Feb;103:13-18. doi: 10.1016/j.ijid.2020.11.150. Epub 2020 Nov 16.
4
Unique class 1 integron and multiple resistance genes co-located on IncHI2 plasmid is associated with the emerging multidrug resistance of Salmonella Indiana isolated from chicken in China.
Foodborne Pathog Dis. 2013 Jul;10(7):581-8. doi: 10.1089/fpd.2012.1455. Epub 2013 May 14.
5
Prevalence and Molecular Characterization of -Positive Salmonella Strains Recovered from Clinical Specimens in China.
Antimicrob Agents Chemother. 2017 Apr 24;61(5). doi: 10.1128/AAC.02471-16. Print 2017 May.
6
Chromosomally and Plasmid-Located in Salmonella from Animals and Food Products in China.
Microbiol Spectr. 2022 Dec 21;10(6):e0277322. doi: 10.1128/spectrum.02773-22. Epub 2022 Nov 21.
7
The characterization of mobile colistin resistance () genes among 33 000 genomes from routine public health surveillance in England.
Microb Genom. 2020 Feb;6(2). doi: 10.1099/mgen.0.000331. Epub 2020 Jan 31.
8
The co-transfer of plasmid-borne colistin-resistant genes mcr-1 and mcr-3.5, the carbapenemase gene bla and the 16S methylase gene rmtB from Escherichia coli.
Sci Rep. 2019 Jan 24;9(1):696. doi: 10.1038/s41598-018-37125-1.
9
Genomic epidemiology of mcr carrying multidrug-resistant ST34 Salmonella enterica serovar Typhimurium in a one health context: The evolution of a global menace.
Sci Total Environ. 2023 Oct 20;896:165203. doi: 10.1016/j.scitotenv.2023.165203. Epub 2023 Jul 3.
10
MDR Salmonella enterica serovar Typhimurium ST34 carrying mcr-1 isolated from cases of bloodstream and intestinal infection in children in China.
J Antimicrob Chemother. 2020 Jan 1;75(1):92-95. doi: 10.1093/jac/dkz415.
引用本文的文献
1
One Health study of mobile colistin resistance () in in Canada, 2017-2022.
Microbiol Spectr. 2025 Jul;13(7):e0215624. doi: 10.1128/spectrum.02156-24. Epub 2025 May 19.
2
Prevalence of Antimicrobial Resistant from Sinking Creek in Northeast Tennessee.
Int J Environ Res Public Health. 2024 Sep 26;21(10):1285. doi: 10.3390/ijerph21101285.
3
Multidrug resistance plasmids underlie clonal expansions and international spread of Salmonella enterica serotype 1,4,[5],12:i:- ST34 in Southeast Asia.
Commun Biol. 2023 Oct 3;6(1):1007. doi: 10.1038/s42003-023-05365-1.
4
Structural biology of MCR-1-mediated resistance to polymyxin antibiotics.
Curr Opin Struct Biol. 2023 Oct;82:102647. doi: 10.1016/j.sbi.2023.102647. Epub 2023 Jul 1.
5
Evidence of international transmission of mobile colistin resistant monophasic Salmonella Typhimurium ST34.
Sci Rep. 2023 May 1;13(1):7080. doi: 10.1038/s41598-023-34242-4.
6
Evolutionary dynamics of multidrug resistant Salmonella enterica serovar 4,[5],12:i:- in Australia.
Nat Commun. 2021 Aug 9;12(1):4786. doi: 10.1038/s41467-021-25073-w.
7
Genomic Characterization of Antimicrobial Resistance in Food Chain and Livestock-Associated Species.
Animals (Basel). 2021 Mar 18;11(3):872. doi: 10.3390/ani11030872.
8
Genetic relatedness of multidrug resistant Escherichia coli isolated from humans, chickens and poultry environments.
Antimicrob Resist Infect Control. 2021 Mar 23;10(1):58. doi: 10.1186/s13756-021-00930-x.
9
Class 1 integron-borne cassettes harboring blaCARB-2 gene in multidrug-resistant and virulent Salmonella Typhimurium ST19 strains recovered from clinical human stool samples, United States.
PLoS One. 2020 Oct 30;15(10):e0240978. doi: 10.1371/journal.pone.0240978. eCollection 2020.
10
A Multidrug-resistant Monophasic Typhimurium Co-harboring in a Transferable IncHI2 Plasmid from a Healthy Catering Worker in China.
Infect Drug Resist. 2020 Oct 13;13:3569-3574. doi: 10.2147/IDR.S272272. eCollection 2020.
本文引用的文献
1
Genome Sequencing of an Escherichia coli Sequence Type 617 Strain Isolated from Beach Ghost Shrimp (Callichirus major) from a Heavily Polluted Ecosystem Reveals a Wider Resistome against Heavy Metals and Antibiotics.
Microbiol Resour Announc. 2019 Jan 17;8(3). doi: 10.1128/MRA.01471-18. eCollection 2019 Jan.
2
Characterization of a colistin-resistant Salmonella enterica 4,[5],12:i:- harbouring mcr-3.2 on a variant IncHI-2 plasmid identified in Canada.
J Med Microbiol. 2018 Dec;67(12):1673-1675. doi: 10.1099/jmm.0.000854. Epub 2018 Oct 23.
3
New Variant of Multidrug-Resistant Serovar Typhimurium Associated with Invasive Disease in Immunocompromised Patients in Vietnam.
mBio. 2018 Sep 4;9(5):e01056-18. doi: 10.1128/mBio.01056-18.
4
Characterization of Highly Prevalent Plasmids Coharboring mcr-1, oqxAB, and bla and Plasmids Harboring oqxAB and bla in Escherichia coli Isolates from Food-Producing Animals in China.
Microb Drug Resist. 2019 Jan/Feb;25(1):108-119. doi: 10.1089/mdr.2017.0391. Epub 2018 Sep 4.
5
A Comparative Genomic Analysis Provides Novel Insights Into the Ecological Success of the Monophasic Serovar 4,[5],12:i:
Front Microbiol. 2018 Apr 17;9:715. doi: 10.3389/fmicb.2018.00715. eCollection 2018.
6
Multidrug-Resistant Salmonella enterica 4,[5],12:i:- Sequence Type 34, New South Wales, Australia, 2016-2017.
Emerg Infect Dis. 2018 Apr;24(4):751-753. doi: 10.3201/eid2404.171619.
7
Towards Understanding MCR-like Colistin Resistance.
Trends Microbiol. 2018 Sep;26(9):794-808. doi: 10.1016/j.tim.2018.02.006. Epub 2018 Mar 7.
8
Salmonella enterica Serotype 4,[5],12:i:- in Swine in the United States Midwest: An Emerging Multidrug-Resistant Clade.
Clin Infect Dis. 2018 Mar 5;66(6):877-885. doi: 10.1093/cid/cix909.
9
Plasmid-borne colistin resistance gene mcr-3 in Salmonella isolates from human infections, Denmark, 2009-17.
Euro Surveill. 2017 Aug 3;22(31). doi: 10.2807/1560-7917.ES.2017.22.31.30587.
10
Novel Plasmid-Mediated Colistin Resistance Gene in .
mBio. 2017 Jun 27;8(3):e00543-17. doi: 10.1128/mBio.00543-17.
Zotero 插件